{"id":2647,"date":"2024-10-23T17:19:05","date_gmt":"2024-10-23T14:19:05","guid":{"rendered":"https:\/\/dergi.fabad.org.tr\/?p=2647"},"modified":"2025-03-25T15:15:23","modified_gmt":"2025-03-25T12:15:23","slug":"2024-volume-49-issue-3","status":"publish","type":"post","link":"https:\/\/dergi.fabad.org.tr\/en\/2024-volume-49-issue-3\/","title":{"rendered":"2024 Volume 49, Issue 3"},"content":{"rendered":"

<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Contents<\/a>, Issue Cover<\/a>, Editorial Board<\/a><\/strong><\/td>\n<\/tr>\n
This issue was published electronically in October 2024.<\/strong><\/td>\n<\/tr>\n
\n

CONTENT\u00a0<\/strong><\/h2>\n

Research Articles<\/strong><\/td>\n

49-3<\/a>
\n\"\"<\/strong><\/td>\n<\/tr>\n
\n
\n<\/td>\n<\/tr>\n
Evaluation of the Genotoxic Impurities of Selpercatinib
\nThrough HPLC and LC-MS\/MS Identification of
\nSelpercatinib Stress Degradation Products<\/strong>Bheemireddy DIVYA*, J Murali PRAKASH**, Eevana Venkata CHIRANJEEVI***,
\nBhaskara Rao TADIBOINA****\u00b0<\/p>\n

* ORCID: , Department of Chemistry, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur – 522302, A.P., India
\n** ORCID: , Department of Chemistry, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur – 522302, A.P., India
\n*** ORCID: , Department of Organic Chemistry, Sri Y.N.M College (Autonomous), Narsapur – 534275, AP, India
\n**** ORCID: , Department of Chemistry, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur – 522302, A.P., India<\/p>\n

\u00b0 Corresponding Author; Bhaskara Rao Tadiboina
\nE-mail: tbhaskararao@gmail.com<\/p>\n

Sayfalar 449-464, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (514 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
The Local Anesthetic Activity of 4-(Naphthalen-1-yloxy)But-2-yn-1-
\nyl)-Containing Piperidine Derivatives in Experimental Animal Models<\/strong><\/p>\n

Malika KHAIITOVA*\u00b0, Yelena SYCHEVA**\u00b0, Vasiliy TRUBACHEV***, Elmira
\nSATBAYEVA****, Valentina YU*****, Talgat NURGOZHIN******, Edgaras STANKEVI\u010cIUS*******, Yeskendir GASSANOV********, Zauresh UTELBAYEVA*********, Khaidar TASSIBEKOV**********<\/p>\n

* ORCID: 0000-0001-6775-4358, Department of Pharmacology, Faculty of General Medicine -1, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
\n** ORCID: 0000-0002-8409-2672, Laboratory of Physiologically Active Compounds chemistry, A.B. Bekturov Institute of Chemical Sciences, Almaty, Republic of Kazakhstan.
\n*** ORCID: 0000-0002-8317-7914, Department of Pharmacology, Faculty of General Medicine -1, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
\n**** ORCID: 0000-0002-5521-5776, Department of Pharmacology, Faculty of General Medicine -1, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
\n***** ORCID: 0000-0001-6508-707X, Laboratory of Synthetic and Natural Medicinal Compounds Chemistry, A.B. Bekturov Institute of Chemical Sciences, Almaty, Republic of Kazakhstan.
\n****** ORCID: 0000-0002-8036-604X, Department of Pharmacology, Faculty of General Medicine -1, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
\n******* ORCID: 0000-0003-2210-708X, Institute of Physiology and Pharmacology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
\n******** Orcid: 0000-0002-4184-4758, Department of Pharmacology, Faculty of General Medicine -1, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
\n********* ORCID: 0000-0003-4312-9093, Faculty of General Medicine -2, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
\n********** ORCID: 0000-0002-1067-5162, Laboratory of Synthetic and Natural Medicinal Compounds Chemistry, A.B. Bekturov Institute of Chemical Sciences, Almaty, Republic of Kazakhstan.<\/p>\n

\u00b0 Corresponding Author; Malika Khaiitova
\nE-mail: khaiitova.m@kaznmu.kz
\nYelena Sycheva
\nE-mail: yelena-sycheva@yandex.kz<\/p>\n

Sayfalar 465-480, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (975 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
Assessment of the Antioxidant, Antiproliferative and Antityrosinase Potential of Unripe Fruit of Prunus x domestica<\/em> L.<\/strong>Z\u00fchal BAYRAK\u00c7EKEN G\u00dcVEN*\u00b0, Neslihan YUCE**, A. Ahmet BASARAN***<\/p>\n

* ORCID: 0000-0003-3405-6996, Department of Pharmacognosy, Faculty of Pharmacy, Erzincan Binali Y\u0131ld\u0131r\u0131m University, Erzincan, Turkey
\n** ORCID: 0000-0001-6878-064, Department of Medical Biochemistry, Faculty of Medicine, Ataturk University, Erzurum, Turkey
\n*** ORCID: 0000-0001-8570-9649, Department of Pharmacognosy, Faculty of Pharmacy, Baskent University, Ankara, Turkey<\/p>\n

\u00b0 Corresponding Author; Z\u00fchal Bayrak\u00e7eken G\u00fcven
\nE-mail: zhlbayrakceken@gmail.com<\/p>\n

Sayfalar 481-490, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (311 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
99mTc-Labeled Microsized Liposomes<\/strong><\/p>\n

Helin HEKIMOGLU*+, Merve KARPUZ**\u00b0+, Emre OZGENC***,
\nEvren GUNDOGDU****<\/p>\n

* ORCID ID: 0009-0001-7119-6878. Izmir Katip Celebi University Faculty of Pharmacy, Izmir, Turkey.
\n** ORCID ID: 0000-0001-6681-2448. Izmir Katip Celebi University Faculty of Pharmacy, Department of Radiopharmacy, Izmir, Turkey.
\n*** ORCID ID: 0000-0002-7586-8520. Ege University Faculty of Pharmacy, Department of Radiopharmacy, Izmir, Turkey.
\n**** ORCID ID: 0000-0003-2111-101X. Ege University Faculty of Pharmacy, Department of Radiopharmacy, Izmir, Turkey.<\/p>\n

+ These authors contributed equally.
\n\u00b0 Corresponding Author; Merve KARPUZ,
\ne-mail: merve.karpuz@ikcu.edu.tr<\/p>\n

Sayfalar 491-504, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t<\/strong>, PDF (601 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
A Novel Method for The Simultaneous Determination
\nof Olanzapine and Escitalopram in Artificial Saliva by
\nHigh Performance Liquid Chromatography<\/strong>Aysun D\u0130N\u00c7EL*\u00b0, Selin \u015eAM\u0130L**, E. Damla G\u00d6K-TOPAK***<\/p>\n

* ORCID: 0000-0002-1986-6862: Lokman Hekim University, Faculty of Pharmacy, Department of Analytical Chemistry, 06510, Ankara, T\u00fcrkiye
\n** ORCID: 0009-0005-0650-5477: Lokman Hekim University, Faculty of Pharmacy, Department of Analytical Chemistry, 06510, Ankara, T\u00fcrkiye
\n*** ORCID: 0000-0002-2586-8207: Lokman Hekim University, Faculty of Pharmacy, Department of Analytical Chemistry, 06510, Ankara, T\u00fcrkiye<\/p>\n

\u00b0 Corresponding Author; Aysun D\u0130N\u00c7EL
\nE-mail: aysun.dincel@lokmanhekim.edu.tr<\/p>\n

Sayfalar 505-512, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t<\/strong>, PDF (387 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
Does Functionality of Perivascular Adipose Tissue Decrease in the Adult Rat Thoracic Aorta?<\/strong>Gaye OZTURK*, Melike Hacer OZKAN**\u00b0<\/p>\n

* ORCID: 0000-0002-2073-7865, Private Mim Hospital, Cankaya, Ankara, Turkiye
\n** ORCID: 0000-0003-1339-2616, Department of Pharmacology, Faculty of Pharmacy, Hacettepe University, Sihhiye, Ankara, Turkiye<\/p>\n

\u00b0 Corresponding Author; Melike Hacer OZKAN
\nE-mail: melikeo@hacettepe.edu.tr<\/p>\n

Sayfalar 513-524, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (283 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
Evaluation of Antioxidant, Cytotoxic Effects and
\nPhytochemical Profiles of Galls Caused by Eriophyidae
\nmite in Juglans regia<\/em> Leaves<\/strong>Semih BULUT*\u00b0, Bur\u00e7in \u00d6Z\u00dcPEK**, Sultan PEKACAR***, Aysun \u00d6ZDEM\u0130R****,
\nDidem DEL\u0130ORMAN ORHAN*****<\/p>\n

* ORCID: 0000-0002-4098-0221, Department of Pharmacognosy, Faculty of Pharmacy, Suleyman Demirel University, Isparta, Turkiye
\n** ORCID: 0000-0003-2159-9860, Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkiye
\n*** ORCID: 0000-0002-7782-9832, Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkiye
\n**** ORCID: 0000-0003-0311-0507, Department of Pharmacology, Faculty of Pharmacy, Gazi University, Ankara, Turkiye
\n***** ORCID: 0000-0003-3916-4048, Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkiye<\/p>\n

\u00b0 Corresponding Author; Semih BULUT
\nE-mail: semihbulut@sdu.edu.tr<\/p>\n

Sayfalar 525-538, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (530 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
A (hetero)arylidene-(4-substituted-thiazol-2-yl) hydrazine As New Potential MAO-B inhibitors. Computational Study and In-Silico Prediction<\/strong>Moulay Ahfid El ALAOUY*, Marwa ALAQARBEH**\u00b0, Abdelouahid SBAI***,
\nHamid MAGHAT****, Tahar LAKHLIFI*****, Mohammed BOUACHRINE******<\/p>\n

* ORCID: 0009-0005-1593-1486 Molecular Chemistry and Natural Substances Laboratory, Faculty of Science, University Moulay Ismail, Meknes, Morocco
\n** ORCID: 0000-0002-0879-5077 Basic Science Department, Prince Al Hussein bin Abdullah II Academy for Civil Protection, Al-Balqa Applied University, Al-Salt 19117, Jordan
\n*** ORCID: 0000-0002-7140-9853 Molecular Chemistry and Natural Substances Laboratory, Faculty of Science, University Moulay Ismail, Meknes, Morocco
\n**** ORCID: 0000-0002-7731-330X Molecular Chemistry and Natural Substances Laboratory, Faculty of Science, University Moulay Ismail, Meknes, Morocco
\n***** ORCID: 0000-0003-4917-475X Molecular Chemistry and Natural Substances Laboratory, Faculty of Science, University Moulay Ismail, Meknes, Morocco
\n****** ORCID: 0000-0002-8901-047X Molecular Chemistry and Natural Substances Laboratory, Faculty of Science, University Moulay Ismail, Meknes, Morocco<\/p>\n

\u00b0 Corresponding Author; Marwa Alaqarbeh,
\nmarwaqarbh@hotmail.com; marwa.aqarbeh@bau.edu.jo<\/p>\n

Sayfalar 539-564, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (1.835 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
Innovative Approaches in Mirtazapine Delivery: Pharmacokinetic
\nSimulations, Immediate Release to Controlled-Release Tablets,
\nFormulation Optimization via D-optimal Mixture Design<\/strong>Srk Raju SAGIRAJU*\u00b0, Pankaj Kumar SHARMA**, Jaya SHARMA***<\/p>\n

* ORCID: 0009-0003-8844-4633, Research Scholar of Pharmacy, Apex university, Jaipur, Rajasthan,302018, India
\n** ORCID: 0000-0001-7398-2744, Dean of Pharmacy, Apex University, Jaipur, Rajasthan,302018, India
\n*** ORCID:0000-0002-1406-6225, Principal School of Pharmacy, Apex University, Jaipur, Rajasthan, India<\/p>\n

\u00b0 Corresponding Author; SRK Raju Sagiraju
\nE-mail: raaju42@gmail.com<\/p>\n

Sayfalar 565-582, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (584 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
Review Articles <\/strong><\/td>\n<\/tr>\n
\n
\n<\/td>\n<\/tr>\n
The Rise of Artificial Intelligence in Pharma: Shaping
\nthe Future of Drug Discovery<\/strong>Ayca DEDEOGLU-ERDOGAN*\u00b0, Armanc MAT**, Enise Ece GURDAL***,
\nMeric KOKSAL****<\/p>\n

* ORCID: 0000-0001-5936-5328, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, Atasehir, 34755 Istanbul, Turkey
\n** ORCID: 0009-0001-8379-3987, Faculty of Pharmacy, Yeditepe University, Atasehir, 34755 Istanbul, Turkey
\n*** ORCID: 0000-0003-1064-8639, Department of Organic Chemistry, Faculty of Chemistry, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany
\nDepartment of Nano-optics, Max Planck Institute for the Science of Light, 91058, Erlangen, Germany
\n**** ORCID: 0000-0001-7662-9364, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, Atasehir, 34755 Istanbul, Turkey<\/p>\n

\u00b0 Corresponding Author; Ayca DEDEOGLU-ERDOGAN,
\nE-mail: elifaycadedeoglu@gmail.com<\/p>\n

Sayfalar 583-602, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (1.103 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
An Overview of Synthetic Derivatives of Thiazole and
\nTheir Role in Therapeutics<\/strong>Manoj KASHYAP*, Muslek Uddin MAZUMDER**\u00b0, Pooja PATOWARY***,
\nApurba TALUKDAR****, Bhargab Jyoti SAHARIAH*****, Manish MAJUMDER******<\/p>\n

*ORCID: 0000-0002-9675-8646, Department of Pharmaceutical Chemistry, NETES Institute of Pharmaceutical Science (NEMCARE Group of Institutions), Kamrup, Assam, India.
\n** ORCID: 0000-0002-1540-3086, Research Scholar, Assam Science and Technology University, Guwahati, Assam, India.
\n*** ORCID: 0000-0002-0476-2868, Department of Pharmaceutical Chemistry, NETES Institute of Pharmaceutical Science (NEMCARE Group of Institutions), Kamrup, Assam, India.
\n**** ORCID: 0000-0001-9538-2512, Department of Pharmaceutics, NETES Institute of Pharmaceutical Science (NEMCARE Group of Institutions), Kamrup, Assam, India.
\n***** ORCID: 0000-0003-0440-6983, Department of Pharmaceutics, NETES Institute of Pharmaceutical Science (NEMCARE Group of Institutions), Kamrup, Assam, India.
\n****** ORCID: 0000-0001-8035-7429, Department of Pharmaceutical Chemistry, NETES Institute of Pharmaceutical Science (NEMCARE Group of Institutions), Kamrup, Assam,
\nIndia.<\/p>\n

\u00b0 Corresponding Author; Muslek Uddin MAZUMDER
\nE-mail: muslekm@gmail.com<\/p>\n

Sayfalar 603-626, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (519 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
Ocular Drug Delivery Routes: Diseases Overview and
\nAdvanced Administration Methods<\/strong>Ceren YETGIN*, Fatma Nur TU\u011eCU-DEM\u0130R\u00d6Z**, Sevgi TAKKA***\u00b0<\/p>\n

* ORCID: 0000-0001-6451-0497, Gazi University Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Turkey.
\n** ORCID: 0000-0002-9468-3329, Gazi University Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Turkey.
\n*** ORCID: 0000-0003-4429-9836, Gazi University Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Turkey.<\/p>\n

\u00b0 Corresponding Author; Sevgi TAKKA
\nE-mail: takka@gazi.edu.tr<\/p>\n

Sayfalar 627-646, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (609 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n
Nanomaterials Marvels: Transformative Advancements
\nin Biomedicine, Drug Delivery, and Pharmaceutical
\nAnalysis<\/strong>Amaresh PRUSTY*\u00b0, Sasmita Kumari PADH\u0130**<\/p>\n

* ORCID: 0000-0002-2978-8044, Department of Pharmaceutics, Royal College of Pharmacy and Health Sciences, Berhampur. Odisha. India.
\n** ORCID: 0009-0009-7989-1021, College of Nursing. MKCG College. Berhampur. Odisha. India.<\/p>\n

\u00b0 Corresponding Author; Dr. Amaresh Prusty
\nE-mail: amareshprusty@gmail.com<\/p>\n

Sayfalar 647-658, \t\t\r\n\t\tAbstact\t\t<\/a>\r\n\t\t, PDF (185 KB)<\/a><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/p>","protected":false},"excerpt":{"rendered":"

Contents, Issue Cover, Editorial Board This issue was published electronically in October 2024. CONTENT\u00a0 Research Articles 49-3 Evaluation of the Genotoxic Impurities of Selpercatinib Through HPLC and LC-MS\/MS Identification of Selpercatinib Stress Degradation ProductsBheemireddy DIVYA*, J Murali PRAKASH**, Eevana Venkata CHIRANJEEVI***, Bhaskara Rao TADIBOINA****\u00b0 * ORCID: , Department of Chemistry, Koneru Lakshmaiah Education Foundation, Vaddeswaram,…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32],"tags":[],"class_list":["post-2647","post","type-post","status-publish","format-standard","hentry","category-issue"],"_links":{"self":[{"href":"https:\/\/dergi.fabad.org.tr\/en\/wp-json\/wp\/v2\/posts\/2647","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dergi.fabad.org.tr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dergi.fabad.org.tr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dergi.fabad.org.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dergi.fabad.org.tr\/en\/wp-json\/wp\/v2\/comments?post=2647"}],"version-history":[{"count":7,"href":"https:\/\/dergi.fabad.org.tr\/en\/wp-json\/wp\/v2\/posts\/2647\/revisions"}],"predecessor-version":[{"id":2715,"href":"https:\/\/dergi.fabad.org.tr\/en\/wp-json\/wp\/v2\/posts\/2647\/revisions\/2715"}],"wp:attachment":[{"href":"https:\/\/dergi.fabad.org.tr\/en\/wp-json\/wp\/v2\/media?parent=2647"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dergi.fabad.org.tr\/en\/wp-json\/wp\/v2\/categories?post=2647"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dergi.fabad.org.tr\/en\/wp-json\/wp\/v2\/tags?post=2647"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}