BIOAVAILABILITY
FILE: PIRIBEDIL
Müzeyyen
DEMÝREL*°,Yasemin YAZAN*
*Anadolu
Üniversitesi,Eczacilik Fakültesi,Farmasötik
Teknoloji Anabilim Dali,26470 ESKISEHIR
°Correspondence
Summary:
Piribedil is a dopamin agonist with vasodilator activity
and whose aqueous solubility is low and elimination half-life
is short.It is widely used in cerebral ageing and in Parkinson's
disease.Literature on physico-chemical and pharmacological
properties, analysis methods, bioavailability and pharmacokinetics
of piribedil has been reviewed in this artcle.
Keywords:
Piribedil, physico-chemical characteristics, bioavailability,
pharmacokinetics.
