Zeliha S.AKDEMİR*, İ.İrem TATLI*, Erdal BEDİR**1, İkhlas A. KHAN**

*Hacettepe University, Faculty of Pharmacy, Depatment of Pharmacognosy, 06100 Sıhhiye, Ankara, TURKEY.
**National Center for Natural Products Research Institude of Pharmaceutical Sciences, University of Mississippi, Mississippi 38677, USA.
1Present Addres: Ege University,Faculty of Engineering,Department of Bioengineering, 35100 Bornova, İzmir, TURKEY.

Summary:
Phenolic natural products such as flavonoids are known as potential antioxidant compounds. The aim of this study was isolation, structure elucidation and determination of radical scavenging properties of flavonoids which were quided by DPPH autographic assay from the methanolic extract of the aerial parts of Verbascum salviifolium.From the titled plant,four flavonoid glucosides, apigenin-7-O-ß-glucopyranoside (1), luteolin-7-O-ß-glucopyranoside (2), luteolin-3’-O-ß-glucopyranoside (3), and chyysoeriol-7-O-ß-glucopyranoside (4), were isolated. The structures of the compounds were esthablıshed on the basis of the spectroscopic evidence. Compounds 1-4 demonstrated scavenging properties toward the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical in TLC autographic assays.