History
 

FABAD  J. Pharm. Sci.
ISSN 1300-4182
Copyright Ó 2006 FABAD. All rights reserved 

FABAD J. Pharm. Sci., 31(4), 198-209, 2006. PDF(1.971 KB)

Research Articles

ABSTRACT

Decontamination of Cosmetic Products and Raw Materials by Gamma Irradiation
Neslihan NAKİ SİVRİ*, A. Yekta ÖZER*,
°, Meral ÖZALP**, Nilgün ATAKAN***, Mustafa POLAT
* Hacettepe University, Faculty of Pharmacy, Department of Radiopharmacy, 06100, Ankara,Turkey.
** Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Microbiology, 06100, Ankara, Turkey.
*** Hacettepe University, Faculty of Medicine, Department of Dermatology, 06100, Ankara, Turkey.
**** Hacettepe University, Faculty of Engineering, Department of Physics Engineering, 06532, Ankara, Turkey.


oCorresponding Author

Summary


In this study, we aimed to use gamma irradiation for decontamination of cosmetic products in order to achieve the acceptable microbiological limits. Cosmetic products and raw materials were irradiated (5-7.5-10 kGy) and physicochemical, microbiological and biological properties of these samples were evaluated in normal and stress storage conditions. It was found that the physicochemical properties of samples tested were changed after irradiation. No change was observed in skin irritation properties of all samples tested. Decontamination dose for all samples, excluding starch, was found to be about 5 kGy or below.

Key Words :
Decontamination by gamma radiation, cosmetic products, cosmetic raw materials.