Free Radical
Scavenging and Antimicrobial Activities of Three Geranium
Species Growing in Turkey
Didem ÞÖHRETOÐLU*,o,
M. Koray SAKAR*, Melike EKÝZOÐLU**, Meral ÖZALP**
*Hacettepe University, Faculty of Pharmacy, Department of
Pharmacognosy, Ankara, Turkey
**Hacettepe University, Faculty of Pharmacy, Department of
Pharmaceutical Microbiology, Ankara, Turkey
oCorresponding Author
Summary
Antimicrobial and free radical scavenging activities of
EtOAc, n-BuOH and the remaining H2O extracts of aerial parts
of
Geranium glaberrimum Boiss et Heldr. Geranium stepporum
Davis and Geranium psilostemon Ledeb were investigated in
this study. Broth microdilution and spectrophotometric DPPH
methods were used to test antimicrobial and free radical
scavenging activity, respectively. All tested extracts
showed free radical scavenging activity. The EtOAc extracts
of all studied plants were found to possess the highest
antimicrobial and free radical scavenging activity. Among
the tested extracts, the EtOAc extract of G. psilostemon is
considered the most active against the tested
microorganisms. All EtOAc extracts were shown to possess
higher free radical scavenging activity than that of
ascorbic acid at 50 μg/mL.
Key Words :
Geranium, Geranium glaberrimum, Geranium
stepporum, Geranium psilostemon, Geraniaceae, antimicrobial
activity, free radical scavenging activity.
