Antibacterial and Antifungal Activities of Some Quercus
Species Growing in Turkey
Didem ÞÖHRETOÐLU*,o, Melike EKÝZOÐLU**, Ekrem KILIÇ**, M.
Koray SAKAR*
* Hacettepe University, Faculty of Pharmacy, Department of
Pharmacognosy, Ankara, Turkey
** Hacettepe University, Faculty of Pharmacy, Department of
Pharmaceutical Microbiology, Ankara, Turkey
oCorresponding Author
Summary
In this study, antibacterial and antifungal activities of
Quercus macranthera subsp. syspirensis, Q. cerris, Q.
pubescens, and Q. coccifera were investigated using broth
microdilution method by measuring minimum inhibitory
concentrations (MICs) of the different extracts.
Antimicrobial activity was determined against two
Gram-positive and two Gram-negative bacteria and for three
fungi. All of the extracts possessed more antifungal
activity than antibacterial activity in general. Almost all
extracts were found to be active against the tested Candida
strains. In particular, n-BuOH extract of Q. coccifera
exhibited significant activity against C. parapsilosis, with
a MIC value of 4.8 μg/ml.
Key Words
Quercus, Fagaceae, oak, antimicrobial activity
