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FABAD  J. Pharm. Sci.
ISSN 1300-4182
Copyright Ó 2011 FABAD. All rights reserved 

FABAD J. Pharm. Sci., 36(1), 11-15, 2011. PDF (437 KB)

Research Articles

ABSTRACT

Antimicrobial Activity of Some Verbascum Species Growing in Turkey
 
Çiğdem KAHRAMAN*, Melike EKIZOĞLU**, Didem KART**, Zeliha Ş. AKDEMIR*, I. Irem TATLI***,°
 * Hacettepe University, Faculty of Pharmacy, Department of Pharmacognosy, Ankara, Turkey
 ** Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Microbiology, Ankara, Turkey
 *** Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Botany, Ankara, Turkey.


 ° Corresponding Author E-mail: itatli@hacettepe.edu.tr



Summary


The antimicrobial activities of methanol extracts of seven Verbascum species were studied. The dried extracts of the aerial parts of Verbascum dudleyanum (Hub.-Mor.) Hub.-Mor., V. latisepalum Hub.-Mor., V. mucronatum Lam., V. olympicum Boiss., V. stachydifolium Boiss. & Heldr. and V. uschackense (Murb.) Hub.-Mor., the flowers of V. lasianthum Boiss. were tested against standard bacterial strains of Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Staphylococcus aureus (ATCC 29213), Enterococcus faecalis (ATCC 29212), and standard fungal strains of Candida albicans ATCC 90028, Candida parapsilosis ATCC 90018 and Candida krusei ATCC 6258 by disc diffusion methods, which were recommended by Clinical and Laboratory Standards Institute. While V. mucronatum Lam. and V. olympicum Boiss. showed an antibacterial activity against gram positive bacteria, and S. aureus as well as V. latisepalum Hub.-Mor. showed an antifungal activity against C. krusei. The other species had no activity.

Key Words :
Verbascum dudleyanum, V. lasianthum, V. latisepalum, V. mucronatum, V. olympicum, V. stachydifolium, V. uschackense, Scrophulariaceae, Antimicrobial Activity.