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FABAD  J. Pharm. Sci.
ISSN 1300-4182
Copyright Ó 2013 FABAD. All rights reserved 

FABAD J.Pharm. Sci.,42, 2, 81-86 PDF (328 KB)

Research Articles

ABSTRACT

Evaluation of the Antioxidant Potential and Chlorogenic Acid Contents of Three Endemic Sideritis Taxa from Turkey

Alper GÖKBULUT*°, Ayŝe Nur YAZGAN*, Hayri DUMAN**, Betül SEVER YILMAZ*

* Ankara University, Faculty of Pharmacy, Department of Pharmacognosy, 06100, Ankara, Turkey
** Gazi University, Faculty of Science and Literature, Department of Biology, 06500, Ankara, Turkey

° Corresponding Author:
Tel: 0312 203 30 87,
Fax: 03122131081,
E-mail address: gokbulut@pharmacy.ankara.edu.tr

Summary

In the present study, the endemic Sideritis argyrea, S. congesta and S. erythrantha var. cedretorum methanol extracts from the dried aerial parts were evaluated for their antioxidant potential and total phenolic content. Also, one of the major constituents, chlorogenic acid was quantified using a previously validated HPLC method. The highest total phenolic content was determined in S. erythrantha var. cedretorum as 190.78±2.46 mg GAE/g; whereas, the highest antioxidant activity results were obtained for S. erythrantha var. cedretorum by using both DPPH and ABTS assays. Chlorogenic acid contents of the S. argyrea, S. congesta, and S. erythrantha var. cedretorum were determined as 0.196±0.01 g/100g dw, 0.289±0.007 g/100g dw, and 0.282±0.01 g/100g dw, respectively. Sideritis taxa with particular high total phenolic content and antioxidant potential can be addressed as a chlorogenic acid source.


Key Words :
Sideritis, DPPH, ABTS, Folin, Lamiaceae, HPLC,