Secondary Metabolites of Achillea sintenisii HUB. MOR.

Selman ŞABANOĞLU*°, Elian KHAZNEH**, Gülçin SALTAN*,
Mehmet TEKİN***, Burçin ERGENE*, Özlem BAHADIR ACIKARA*,

* Ankara University, Faculty of Pharmacy, Department of Pharmacognosy, 06100, Tandoğan-Ankara, TURKEY
** University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Pharmacy, Department of Natural Drugs, Brno, CZECH REPUBLIC
*** Cumhuriyet University, Faculty of Pharmacy, Department of Pharmaceutical Botany, 58140, Sivas, TURKEY

° Corresponding Author:
Tel: 0312 203 30 97,
Fax: 0312 213 10 81,
E-mail address: sabanoglu@ankara.edu.tr

 

Summary

Achillea species (Asteraceae) are represented by approximately140 species in the world. In folk medicine, these species are used as herbal remedies due to their anti-inflammatory, analgesic, antispasmodic, digestive, wound healing, hemostatic and cholagogue effects. Flavonoids represent an important group of bioactive components in Achillea species. It has been reported that flavonoids, such as apigenin, luteolin, quercetin, and their glycosides as well as methyl derivatives have been isolated from different species of Achillea. Achillea sintenisii Hub. Mor. is an endemic species and distributed in central Anatolia. Phenolic composition of the aerial part extracts of A. sintenisii were investigated in current study by HPLC analysis on a SUPELCOSILTM ABZ+PLUS, 15 cm x 4.6 mm column using standard compounds.

Key Words :
Achillea sintenisii, phenolic compounds, HPLC