OXIMES AND OXIME ETHERS: II. CHEMICAL AND SPECTRAL PROPERTIES

Arzu KARAKURT*, Sevim DALKARA*°

*Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 06100 Sihhiye, Ankara, TURKEY.
°Corresponding Author

Summary :
Oximes are derived from the reaction of aldehydes or ketones with hydroxylamine and show E/Z isomerism due to the carbon-nitrogen double bond in their structure. Many drugs in the market today have oxime or oxime ether groups in their structure and these groups are frequently used for molecular modification to develop new drugs and for synthesis of many functional groups as starting compounds. Chemical and spectral properties of these important groups have been reviewed in this article.

Key words:
Oxime, Oxime ether, Chemical properties, Spectral properties.