Sibel BOZDAĞ*, İmran VURAL*, Yılmaz ÇAPAN*,?, Turgay DALKARA**

*Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology, 06100 Sıhhiye, Ankara, TURKEY.
**Hacettepe University, Faculty of Medicine, Department of Neurology, 06100 Sıhhiye Ankara, TURKEY.
oCorresponding author

Summary:
The incidence of brain tumors increased dramatically in recent years. Brain tumor is the second major cause of neurologic deaths and causes 2 percent of all cancer deaths.The overall median survival time after treatment of brain tumors with surgery and radiation therapy is eight to nine months. Therefore, research efforts are expanding to find new methods for the treatment of these patients.In this review, recent developments in immunotherapy , gene therapy, phototherapy, chemotherapy, radiotherapy and implants for drug delivery to brain tumors are discussed, and recent literature on the treatment of brain tumors is presented.