History
 

FABAD  J. Pharm. Sci.
ISSN 1300-4182
Copyright Ó 2005 FABAD. All rights reserved 

FABAD J. Pharm. Sci., 28(1), 51-58, 2003.PDF (292 KB)

Scientific Reviews

ABSTRACT

ACETYLCHOLINESTERASE INHIBITORS FROM NATURAL RESOURCES

Ýlkay ORHAN*,o, Bilge ÞENER*

*Gazi University, Faculty of Pharmacy, Department of Pharmacognosy, 06330 Hipodrom, Ankara, TURKEY.
oCorresponding Author

Summary:
Acetylcholinesterase inhibitors reduction of acetylcholine via inhibiting acetylcholinesterase enzyme which hydrolyzes acetycholine in neuronal and from which it is released. Acethylcholinesterase inhibitors play an important role in the treatment of Alezheimer’s Disease as well as Myasthenia Gravis, Glaucoma and Helminthiasis together with the mecanism of action of insecticide drugs.
In this review, some compounds obtained from natural resources that have acetylcholineesterase inhibitory activity are evaluated.

Keywords:
Acetylcholinesterase, Alzheimer’s Disease, Acetylcholinesterase inhibitory activity, Plant.