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FABAD
J. Pharm. Sci.
ISSN 1300-4182
Copyright Ó 2005
FABAD. All rights reserved
FABAD
J. Pharm. Sci., 29(4), 169-175, 2004. PDF
(802 KB)
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Research
Articles
ABSTRACT
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SCREENING
FOR ALCOHOL AND DRUGS OF ABUSE IN TRAUMA VICTIMS
Banuçiçek
YÜCESAN*, Þebnem Þ. ÇEÇEN**,
Yücel DENER***, Rüçhan ÖZTÜRK***,
Yaþar BÝLGE****,
Tülin SÖYLEMEZOÐLU**o
* Refik Saydam Hygiene Center, Blood and Blood Products
Quality Control Laboratory, 06100 Sýhhiye, Ankara
- TURKEY.
** Ankara University, Institute of Forensic Medicine,
06260, Dikimevi, Ankara-TURKEY.
***
The Rebuplic of Turkey, Ministry of Justice, Council of
Forencis Medicine, Chemistry Department, Ankara - TURKEY.
**** Ankara University, Faculty of Pharmacy, Department
of Forensic Medicine, Dikimevi, Ankara- TURKEY.
oCorresponding Author
Summary
The objective of this study was to evaluate the relationship
between alcohol/drug abuse and injury severity caused by
trauma.
Toward this aim, routinely collected urine and blood specimens
from 102 trauma patients were analyzed for the presence
of drugs of abuse by an enzyme immunoassay method, CEDIA
® DAU, and for alcohol by headspace gas chromatography.
To predict recovery, to assess the patient’s condition
and to determine the possible correlation between alcohol/drug
abuse and injury severity, trauma score (TS), Glasgow coma
scale (GCS) and % probability of survival were calculated.
Our results de-monstrated that male patients were more likely
to use drugs and consume alcohol than female patients (p=
0.001). Trauma victims with severe and fatal injuries having
low TS and GCS with low probability of survival were more
likely to have positive screens (p=0.000) and higher blood
alcohol levels (p=0.000) than those with less severe injuries.
However, no significant relationship was found between alcohol/drug
abuse and trauma reasons (p=0.061) or between trauma reasons/sex
(p=0.078)
Key Words :
Alcohol and abused drugs, trauma score, Glasgow
coma scale, CEDIA ® DAU, headspace gas chromatography
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