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FABAD  J. Pharm. Sci.
ISSN 1300-4182
Copyright Ó 2005 FABAD. All rights reserved 

FABAD J. Pharm. Sci., 29(4), 203-210, 2004. PDF (1.478 KB)

Scientific Reviews

ABSTRACT

Invited Review: INVESTIGATION OF ANTIOXIDATIVE COMPOUNDS FROM OIL PLANT SEED
Akito NAGATSU*
o
* College of Pharmacy, Kinjogakuin University, 2-1723 Ohmori, Moriyama-ku, Nagoya 463-8521 JAPAN.

oCorresponding Author

Summary
Antioxidative compounds in rape, safflower, and cotton seed oil cakes were investigated in order to find more potent and safer antioxidants for use in food additives or functional food. Six compounds were isolated from rape seed oil cake, nine from safflower, and five from cotton, by assaying DPPH radical scavenging activity and the inhibitory activity on lipid peroxidation. Inhibitory activity on AGEs production and supercoiled DNA strand scission preventing activity were also evaluated as other antioxidative activities in major compounds from safflower seed oil cake. The safflower seed oil cake has the potential to become a good source of antioxidative compounds because it contained a significant amount of antioxidative compounds and their glucosides.

Key Words :
Antioxidative compounds, rape seed, safflower seed, cotton seed, DPPH radical scavenging activity, inhibition of lipid peroxidation, inhibition of AGEs, supercoiled DNA strand scission preventing activity.