History
 

FABAD  J. Pharm. Sci.
ISSN 1300-4182
Copyright Ó 2010 FABAD. All rights reserved 

FABAD J. Pharm. Sci., 35(1), 29-35, 2010. PDF (517 KB)

Research Articles

ABSTRACT

Iridoid and Megastigman Glucosides from Plantago lagopus L.

Yasin GENÇ*, İclal SARAÇOĞLU*, Akito NAGATSU**, Ü. Şebnem HARPUT*,°
* Hacettepe University, Faculty of Pharmacy, Department of Pharmacognosy, TR-06100 Ankara-TURKEY
** College of Pharmacy, Kinjo Gakuin University, Ohmori 2-1723, Nagoya 463–8521, Japan.


oCorresponding Author: sharput@hacettepe.edu.tr

Summary


Two iridoid glucosides, catalpol and aucubin, one chlorinated iridoid aglycon, rehmaglutin D were isolated from the iridoid fraction of the aerial parts of Plantago lagopus L. together with the megastigman glucoside, phlomuroside. The structures of the isolated compounds were identified by means of spectroscopic (UV, HR-ESI, 1H-NMR, 13C NMR, HMQC, HMBC, COSY) methods. This is the first report for the first isolation of rehmaglutin D and phlomuroside from the genus Plantago.

Key Words :
Plantago, iridoid glucoside, rehmaglutin D, phlomuroside, catalpol, aucubin.