Avarone and Avarol from The Marine Sponge Dysidea avara Schmidt from Marmara Coast of Turkey
Nihal AKTAŞ*, Bülent GÖZCELIOĞLU**, Yang ZANG***, Wen-Han LIN, Belma KONUKLUGIL*^,°

* Department of Pharmacognosy, Faculty of Pharmacy, Ankara University, Ankara, Turkey
** Bülent Gözcelioğlu, Scientific and Technological Research Council of Turkey (TÜBİTAK), Ankara, Turkey.
*** State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, P.R.China
° Corresponding Author E-mail: belmakonuk@yahoo.com

Summary

Turkish coastline is almost 8400 km long in total. The sponges found in the seas surrounding Turkey have not yet been intensively studied. During the course of our studies on Turkish marine sponges, we have isolated avarol and avarone from Dysidea avara (family Dysideidae, order Dictyoceratida) collected in İbrice, on the Aegean coast. Chemical investigation of methanolic extract of the sponges led to identification of avarol and avarone. Their structures were determined through analyses by 1H and 13C NMR spectroscopic data.

Key Words :
Marine sponge, Dysidea avara, avarone and avarol.