Pavel KOHOUT *o, Iva HOSKOVÁ** , Marian SENKERIK*** , Zdenek ZADÁK*

*Department of Metabolic Care and Gerontology, **Solvay Pharma, ***Department of Pediatry, Universty Hospital, Charles University, Hradec Králové, Czech Republic.
o Correspondence

Summary:
The intestinal barrier plays an important role in the pathogenesis of some gastroenterological diseases and its examination can be used in diagnosis and monitoring of some diseases and their course. Sugar absorption tests are non-invasive and non-expensive methods for examination of the intestinal barrier , namely for the measurement of intestinal permeability.
Intestinal permeability is increased in patients with untreated celiac disease , with both the active inflammatory bowel diseases – Crohn’s disease and ulcerative colitis , with exocrine pancreatic insufficiency and drugs induced enteropathy , i.e.non-steroidal anti-inflammatory drug induced enteropathy.

Key words:
Nucleosides, Anti-hepatitis Agents. HBV