History
 

FABAD  J. Pharm. Sci.
ISSN 1300-4182
Copyright Ó 2005 FABAD. All rights reserved 

FABAD J. Pharm. Sci., 28(1), 13-17, 2003. PDF (315 KB)

Research Articles

ABSTRACT

HIGH PERFORMANCE LIQUID CHOROMATOGRAPHIC ANALYSIS OF SOME DITERPENOIDS OF THE BALLOTA SPECIES:

Betül Sever YILMAZ*,Gülçin Saltan Çitoğlu*,o

*Ankara University, Faculity of Pharmacy, Department of Pharmacognosy ,06100 Tandoğan, Ankara, TURKEY.
oCorresponding Author

Summary:
In this study, the dieterpenoids, namely, hospanolone, ballonigrine and dehydrohispanolone, in 16 ballota taxa growing in Turkey have been determined qualitatively by High Performance Liquid Choromatography (HPLC). Analysis was performed on a normal phase column (Zorbax-CN, 5 ?m, 250 x 4.6 mm i.d.). The solvent system consisted of n-Hexane-MeOH (98:2, speed gradient). Peak were detected at 190-360 nm using Photo-diode array (PDA) dedector. The extracts of Ballota acetabulosa, B. Pseudodictamnus subsp. lyca, B. cristata. B. inaequidents, B. saxatilis subsp. saxatilis, B. saxatilis subspbrachyodonta , B. larendana,. B. latibracteolata, B. rotundifolia, B. macrodonta, B. nigra subsb. foetida , B. nigra subsp. unicinata and B. antalyense were found to contain the dierterpenoids.

Keywods:
HPLC analysis, Diterpenoids, Ballota, Lamiaceae.