2024 Volume 49, Issue 2

Contents, Issue Cover, Editorial Board
This issue was published electronically in August 2024.

CONTENTS

Research Articles

49-2

Radiolabeling, Characterization, and In Vitro Cell Culture Studies of Donepezil-Loaded Niosome Formulations For Brain Imaging

Emre OZGENC*°, Hande AYDIN**, Zeynep SENYIGIT***, Evren ATLIHAN GUNDOGDU****

* ORCID: 0000-0002-7586-8520, Department of Radiopharmacy, Faculty of Pharmacy, Ege University, Izmir, Turkey.
** ORCID: 0000-0002-4296-3628, Department of Pharmaceutical Technology, Faculty of Pharmacy, Izmir Katip Celebi University, Izmir, Turkey.
*** ORCID: 0000-0002-4920-2469, Department of Pharmaceutical Technology, Faculty of Pharmacy, Izmir Katip Celebi University, Izmir, Turkey.
**** ORCID: 0000-0003-2111-101X, Department of Radiopharmacy, Faculty of Pharmacy, Ege University, Izmir, Turkey.

° Corresponding Author; Emre Ozgenc
E-mail: emre.ozgenc@ege.edu.tr

Pages 263-276, Abstract , PDF (560 KB)

Theoretical Rationale for the Combined Use of Gabapentin and Fingolimod for the Treatment of Multiple Sclerosis Using In Silico Methods

Vitaly LARIONOV*, Olexandr NEFEDOV**, Igor BELENICHEV***, Olexandr KALBUS****, Olena NEFEDOVA*****, Iryna SAMURA******°, Nina BUKHTIYAROVA*******

* ORCID: 0000-0003-2678-4264, Department of Medical Chemistry, Laboratory of Physico-Chemical Pharmacology, A.V. Bogatsky Physico-Chemical Institute
of National Academy of Sciences of Ukraine, Odessa, Ukraine.
** ORCID: 0000-0002-5796-1852, Clinical Department, INTERCHIM, Additional liability company, Dnipro, Ukraine.
*** ORCID: 0000-0003-1273-5314, Department of Pharmacology and Medical Formulation with the Course of Normal Physiology, Medical Faculty No. 1,
Zaporizhzhia State Medical University, Ukraine.
**** ORCID: 0000-0003-0796-4825, Department of Neurology, Medical Faculty, Dnipro State Medical University, Ukraine.
***** ORCID: 0000-0002-1665-9032, Department of Human Anatomy, Clinical Anatomy and Operative Surgery, Medical Faculty, Dnipro State Medical University,
Ukraine.
****** ORCID: 0000-0001-5352-3209, Department of Pharmacology and Medical Formulation with the Course of Normal Physiology, Medical Faculty No. 1,
Zaporizhzhia State Medical University, Ukraine.
******* ORCID: 0000-0003-3499-3111, Department of Clinical Laboratory Diagnostics, Medical Faculty No.2, Zaporizhzhia State Medical University, Ukraine.

° Corresponding Author; Iryna Samura
E-mail: irinasamura77@gmail.com

Pages 277-288, Abstract , PDF (244 KB)

Evaluation of Patients’ Willingness to Use and Pay for Pharmaceutical Care Services in Türkiye

Zehra ALABDULLAH*, Miray ARSLAN**°

* ORCID: 0009-0002-3068-053X: Faculty of Pharmacy, Van Yüzüncü Yıl University, Van, Türkiye
** ORCID: 0000-0003-2786-4610: Department of Pharmacy Management. Faculty of Pharmacy, Van Yüzüncü Yıl University, Van, Türkiye & UCL School of
Pharmacy, London, UK

° Corresponding Author; Miray ARSLAN
E-mail: mirayarslan@yyu.edu.tr

Pages 289-298, Abstract , PDF (141KB)

Linezolid-Loaded Nanoparticle for Topical Administration of Diabetic Foot Treatment: Formulation, In Vitro and Ex Vivo Characterization

Yusuf POLAT*, Husniye Hande AYDIN**, Seda RENCBER***°

* ORCID: 0009-0004-5071-9803, Faculty of Pharmacy, Izmir Katip Celebi University, Cigli 35620, Izmir, Turkey.
** ORCID: 0000-0002-4296-3628, Department of Pharmaceutical Technology, Faculty of Pharmacy, Izmir Katip Celebi University, Cigli 35620, Izmir, Turkey.
*** ORCID: 0000-0003-0172-2120, Department of Pharmaceutical Technology, Faculty of Pharmacy, Izmir Katip Celebi University, Cigli 35620, Izmir, Turkey.

° Corresponding Author; Seda RENCBER
Email Address: seda.rencber@ikcu.edu.tr

Pages 299-316, Abstract , PDF (1064 KB) 

Linker and Tail Group Modifications on 2-((4-isopropyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-phenoxyphenyl) Acetamide to Improve SIRT2 Inhibitory Potency

Mahmut GOZELLE*, Yesim OZKAN**, Gokcen EREN***°

* ORCID: 0000-0003-0234-6577, SIRTeam Group, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gazi University, 06330 Ankara, Türkiye.
** ORCID: 0000-0002-1669-4962, Department of Biochemistry, Faculty of Pharmacy, Gazi University, 06330 Ankara, Türkiye.
*** ORCID: 0000-0002-3420-607X, SIRTeam Group, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gazi University, 06330 Ankara, Türkiye.

° Corresponding Author; Gokcen EREN
E-mail address: gokcene@gazi.edu.tr

Pages 317-332, Abstract , PDF (1047 KB) 

Psychiatrists’ and Infectious Disease Physicians’ Awareness and Knowledge Level of Drug-Drug Interactions Between Antiretrovirals and Psychotropics: A Comparative Questionnaire-Based Study

Nadir YALÇIN*°, Ahmet Cağkan İNKAYA**, Emre KARA***, Koray BAŞAR****, Abstractge KARADAĞ*****, Kutay DEMIRKAN******, Serhat ÜNAL*******

* ORCID:0000-0002-2280-8727, Hacettepe University Faculty of Pharmacy, Department of Clinical Pharmacy, Ankara, Türkiye
** ORCID:0000-0001-7943-8715, Hacettepe University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Türkiye
*** ORCID:0000-0002-7034-4787,Hacettepe University Faculty of Pharmacy, Department of Clinical Pharmacy, Ankara, Türkiye
**** ORCID:0000-0003-4798-5305, Hacettepe University Faculty of Medicine, Department of Psychiatry, Ankara, Türkiye
***** ORCID:0000-0003-1372-1555, Bahçeşehir University, School of Medicine, İstanbul, Türkiye and Columbia University, Center for Sustainable Development
of the Earth Institute, New York, USA
****** ORCID:0000-0002-6427-5826, Hacettepe University Faculty of Pharmacy, Department of Clinical Pharmacy, Ankara, Türkiye
******* ORCID:0000-0003-1184-4711, Hacettepe University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Türkiye
° Corresponding Author; Nadir Yalçın,
E-mail: nadir.yalcin@hacettepe.edu.tr

Pages 333-344, Abstract , PDF (154KB) Suplement PDF (105KB)

A Qualitative Study Exploring Self-Management Behavior of Patients with Chronic Kidney Disease During COVID-19

Mehmet Barlas UZUN*º, Gizem GÜLPINAR**, Aysel PEHLİVANLI***, Şule ŞENGÜL****

* ORCID:0000-0003-2975-5290, Department of Pharmacy Management, Gülhane Faculty of Pharmacy, University of Health Sciences, Ankara, Türkiye.
** ORCID: 0000-0001-6720-1235, Department of Pharmacy Management, Faulty of Pharmacy, Gazi University, Ankara, Türkiye.
*** ORCID:0000-0003-3276-0162, Department of Pharmacology, Faculty of Pharmacy, Başkent University Ankara, Türkiye.
**** ORCID: 0000-0003-2831-2682, Department of Nephrology, Faculty of Medicine, Ankara University, Ankara, Türkiye.

° Corresponding Author;Mehmet Barlas UZUN
E-mail: mehmetbarlas.uzun@sbu.edu.tr

Pages 345-358, Abstract , PDF (286KB) 

A Network Toxicology Analysis of the Molecular Pathways and Novel Targets in TCDD-Induced Cardiovascular Toxicity

Fuat KARAKUŞ*º

* ORCID: 0000-0002-5260-3650, Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Van Yuzuncu Yil University, Van/Türkiye
° Corresponding Author; Fuat Karakuş
E-posta: fuatkarakus@yyu.edu.tr

Pages 359-370, Abstract , PDF (1863KB) Suplement PDF (53 KB)

Review Articles

Nanoparticles, Aptamers, and Aptamer-Conjugated Nanoparticles in Cancer Therapy

Muhamad Muhamad AlKRIZ*°, Dima JOUJEH**

* ORCID: 0009-0009-7076-3074, Biotechnology engineering, Faculty of Technical engineering, University of Aleppo, Syria.
** ORCID: 0000-0001-8240-9886, Biotechnology engineering, Faculty of Technical engineering, University of Aleppo, Syria.

° Corresponding Author; Muhamad Muhamad Alkriz:
Email Address: muhamadalkriz@gmail.com.

Pages 371-400, Abstract , PDF (1146KB) 

Cyclic Imides Derivatives: A Potential Scaffold for the Synthesis of Anticonvulsant Agents

Amita Joshi RANA*, Shweta SINGH**°, Mahendra RANA***, Hraday Kant AWASTHI****, Amrita Verma PARGAEIN*****, Himanshu JOSHI******

* ORCID: 0000-0003-1907-4459, Graphic Era Hill University Campus Bhimtal (263136), Uttarakhand, India.
** ORCID: 0009-0008-8410-921X, Rakshpal Bahadur College of Pharmacy, Bareilly (243001), Uttar Pradesh, India.
*** ORCID: 0000-0001-7967-7505, Department of Pharmaceutical Sciences, Sir J.C Bose, Technical Campus, Bhimtal (263136), Kumaun University, Nainital,
Uttarakhand, India.
**** ORCID: 0009-0006-7981-9423, Mahatma Jyotiba Phule Rohilkhand University, Department of Pharmacy, Bareilly (243001), Uttar Pradesh, India.
***** ORCID: 0000-0001-6112-3598, Graphic Era Hill University Campus Bhimtal (263136), Uttarakhand, India.
****** ORCID: 0000-0003-0016-8420, Graphic Era Hill University Campus Bhimtal (263136), Uttarakhand, India.

° Corresponding Author; Shweta SINGH
Email: shwetasingh9627@gmail.com

Pages 401-422, Abstract , PDF (1280 KB)

The Effects of Topical Applications of Momordica charantia Extract on Wound Healing: A Comprehensive Review

Simge AKBULUT*°, Mert PEKCAN**

* ORCID: 0000-0002-9059-3449, Biyokimya Anabilim Dalı, Veteriner Fakültesi, Ankara Üniversitesi, Ankara, Türkiye
** ORCID: 0000-0003-3084-125X, Biyokimya Anabilim Dalı, Veteriner Fakültesi, Ankara Üniversitesi, Ankara, Türkiye.

° Corresponding Author; Simge AKBULUT
E-mail: smggrkk@gmail.com

Pages 423-434, Abstract , PDF (152KB)

Molecularly Targeted Therapies in Breast Cancer: A Traditional Review

Busra Irem SIMSEK *, Hamza HALICI **, Elif CADIRCI ***°

* ORCID: 0000-0002-6296-8258, Ataturk University, Faculty of Medicine, Department of Pharmacology, Erzurum, Turkey.
** ORCID: 0000-0002-2028-6603, Ataturk University, Hinis Vocational Training School, Veterinary Services, Erzurum, Turkey.
*** ORCID: 0000-0003-0836-7205, Ataturk University, Faculty of Medicine, Department of Pharmacology, Erzurum, Turkey.

° Corresponding Author; Elif Cadirci
E-mail: ecadirci@atauni.edu.tr,

Sayfalar 435-448, Abstract , PDF (781KB)