Last Issue

2024 Volume 49, Issue 1

Contents, Issue Cover, Editorial Board
This issue was published electronically in March 2024.

CONTENTS

Research Articles

 49-1

In Silico Target Prediction of 6-Gingerol and Similar Compounds as Potential Anticancer Agents
Nour Osama AL-MASSRI*, Enise Ece GURDAL **°, Gulcin TUGCU ***°* ORCID: 0009-0004-8699-3003, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, 34755 Istanbul, Turkey
** ORCID: 0000-0003-1064-8639, Department of Organic Chemistry, Institute of Chemistry, Martin-Luther-Universität Halle-Wittenberg, 06120 Halle, Germany
*** ORCID: 0000-0002-9750-6563, Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Yeditepe University, 34755 Istanbul, Turkey
° Corresponding Authors; Enise Ece Gurdal; Gulcin Tugcu
e-mail: enise-ece.guerdal@chemie.uni-halle.de; gulcin.tugcu@yeditepe.edu.tr

Pages 1-8, Abstract , PDF (2047 KB) Supplement PDF (1468 KB) 

Mineral contents, Antioxidant and Antimicrobial Activities of Algerian Terfezia claveryi extracts

Hadjira GUENANE*, Boulanouar BAKCHICHE**º, Ramazan ERENLER***, Ilyas YILDIZ****, Asmaa S. MOHAMED*****, Maha A.M. El-SHAZLY******

* ORCID: 0000-0002-3598-5343, Laboratory of Biological and Agricultural Sciences (LBAS), Amar Telidji University, Laghouat 03000, Algeria
** ORCID: 0000-0002-3124-5153, Laboratory of Biological and Agricultural Sciences (LBAS), Amar Telidji University, Laghouat 03000, Algeria
*** ORCID: 0000-0002-0505-3190, Department of Chemistry, Faculty of Arts and Sciences, Tokat, Gaziosmanpasa University, 60240 Tokat, Turkey
**** ORCID: 0000-0003-1254-1069, Department of Chemistry, Faculty of Arts and Sciences, Tokat, Gaziosmanpasa University, 60240 Tokat, Turkey
***** ORCID: 0000-0001-9397-0556, Medicinal Chemistry Department, Theodor Bilharz Research Institute, Kornaish El-Nile, Warrak El-Hadar, Imbaba (P.O. 30), Giza 12411, Egypt
****** ORCID: 0000-0002-8229-449x, Medicinal Chemistry Department, Theodor Bilharz Research Institute, Kornaish El-Nile, Warrak El-Hadar, Imbaba (P.O. 30), Giza 12411, Egypt
° Corresponding Author; Boulanouar BAKCHICHE
E-mail: b.bakchiche@lagh-univ.dz

Pages 19-36, Abstract , PDF (383 KB)

Dipyridamole Cocrystal Tablets with Enhanced Solubility and Dissolution at Intestinal pH

Monika NIJHAWAN*° Sadhna DHYAGALA** , Gunnam SAILAJA***, Rajeswari ALETI****, Trapti SAXENA*****

* ORCID: 0000-0002-3564-0257, GokarajuRangaraju College of pharmacy, Department of Pharmaceutics, Associate Professor, Osmania University, Hyderabad, Telangana, India
** ORCID: 0000-0003-1834-7750, GokarajuRangaraju College of pharmacy, Department of Pharmaceutics, Osmania University, Hyderabad, Telangana, India.

*** ORCID: 0009-0007-2550-4001, GokarajuRangaraju College of pharmacy, Department of Pharmaceutics, Associate Professor, Osmania University, Hyderabad, Telangana, India.
**** ORCID: 0009-0001-8894-9063, GokarajuRangaraju College of pharmacy, Department of Pharmaceutics, Assistant Professor Osmania University, Hyderabad, Telangana, India.
***** ORCID: 0009-0001-8894-9063, G Pulla Reddy College of Pharmacy, Department of Pharmaceutics, Associate Professor, Hyderabad, Telangana, India.

° Corresponding Author; Dr. Monika Nijhawan
E-mail:monika8009@grcp.ac.in

Pages 37-50, Abstract , PDF (1377 KB)

Formulation and Evaluation of Mixed Micelles Containing Quercetin for Inhibiting Intestinal Metabolism of Atorvastatin

Narahari N. PALEI*°, Jayaraman RAJANGAM**, Ramu SAMINENI***, Arghya K DHAR****, Anna BALAJI*****

* ORCID: 0000-0002-2041-1849 , Amity Institute of Pharmacy, Amity University Uttar Pradesh, Lucknow Campus, India
** ORCID: 0000-0002-6367-0365, Shri Venkateshwara College of Pharmacy, Ariyur, Pondicherry, India
*** ORCID: 0000-0002-8652-2883, Department of Pharmaceutics, School of Pharmaceutical Sciences, Sandip University, Mahiravani, Maharashtra, India
**** ORCID: 0000-0003-1081-9143, School of Pharmacy, The Neotia University, Sarisha, West Bengal , India
***** ORCID: 0000-0002-3233-9637, IIMT College of Pharmacy, Greater Noida, Uttar Pradesh, India
° Corresponding Author;Narahari N. PALEI
E-mail: narahari.palei@gmail.com

Pages 51-64, Abstract , PDF (2448 KB)

Development and Evaluation of Pullulan-Based Mouth Dissolving Film of Furosemide

Aafreen SAHA*, Umesh Kumar ATNERIYA**°, Umashankar JOSHI***, Dharmendra SOLANKI****

* ORCID: 0009-0004-7250-8492, BM College of Pharmaceutical Educatipon and Research, Indore (Madhya Pradesh) India
** ORCID: 0000-0003-2402-6048, School of Pharmacy, Devi Ahilya Vishwavidyalaya, Indore (Madhya Pradesh) India
*** ORCID: 0009-0006-5426-867X, Shri Bherulal Pharmacy Institute, Indore (Madhya Pradesh) India
**** ORCID: 0000-0001-7093-5985, BM College of Pharmaceutical Educatipon and Research, Indore (Madhya Pradesh) India
° Corresponding Author;Umesh Kumar ATNERIYA
E-mail: atneriya@gmail.com

Pages 65-80, Abstract , PDF (660 KB)

Investigation of the Effects of Oleuropein on Mouse Detrusor Muscle Contractility

Elif Nur BARUT*°, Ahmet Can OZTURK**, Seckin ENGIN***, Gulin RENDA****

* ORCID: 0000-0003-3284-848X, Department of Pharmacology, Faculty of Pharmacy, Karadeniz Technical University Trabzon, Türkiye.
** ORCID: 0009-0001-6803-4018, Department of Pharmacology, Faculty of Pharmacy, Karadeniz Technical University Trabzon, Türkiye.
*** ORCID: 0000-0002-1982-7820, Department of Pharmacology, Faculty of Pharmacy, Karadeniz Technical University Trabzon, Türkiye.
**** ORCID: 0000-0001-6323-0338, Department of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University Trabzon, Türkiye.
° Corresponding Author; Elif Nur Barut
E-mail: elifgazioglu@ktu.edu.tr

Pages 81-90, Abstract , PDF (401 KB)

Immunosuppressive and Ameliorative Effects of Dietary Combined Herbs Extract of Curcuma zedoaria (Christm.) Roscoe and Phyllanthus niruri L. in DMBA-induced Breast Cancer Mouse Model
Wira Eka PUTRA*, Anoraga Mona Larasati Sekar MENTARI**, Devita RATNASARI***, Dhaniar CHAIRUNNIZA****, Arief HIDAYATULLAH*****, Muhaimin RIFA’I******°* ORCID:0000-0003-4831-3869, Biotechnology Study Program, Department of Applied Sciences, Faculty of Mathematics and Natural Sciences, Universitas Negeri
Malang, East Java, Indonesia.
** ORCID:0000-0002-4187-3671, Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, East Java, Indonesia.
*** ORCID: 0000-0003-3650-9012, Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, East Java, Indonesia.
**** ORCID: 0000-0002-6839-3416, Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, East Java, Indonesia.
***** ORCID: 0000-0003-1929-3635, Health Governance Initiative, United Nations Development Programme Indonesia, Eijkman-RSCM Building, Jakarta, Indonesia
****** ORCID: 0000-0001-5731-2951, Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, East Java, Indonesia.
° Corresponding Author; Muhaimin RIFA’I
E-posta: rifa123@ub.ac.id

Pages 91-110, Abstract , PDF (2601 KB)

Metronidazole Loaded Novel Microemulsion Formulation for Topical Delivery and Characterization With Validated New UPLC Method

Tilbe ÇEVİKELLİ*°, Umay Merve GÜVEN**, Ahmet Alper ÖZTÜRK***

* ORCID: 0000-0002-0881-0644, Department of Pharmaceutical Technology, Faculty of Pharmacy, Cukurova University, Adana, Turkey.
** ORCID: 0000-0003-1547-0817, Department of Pharmaceutical Technology, Faculty of Pharmacy, Cukurova University, Adana, Turkey.
*** ORCID: 0000-0001-9596-0538, Department of Pharmaceutical Technology, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.
° Corresponding Author; Tillbe ÇEVİKELLİ
E-mail: tcevikelli@cu.edu.tr

Pages 111-128, Abstract , PDF (925 KB)

In vitro Evaluation of the Effects of Inula viscosa’s Different Extracts on Wound Healing and Oxidative Stress in Mouse L929 Fibroblast Cell Line

Ahmet HARMANKAYA*°, İrfan ÇINAR**, Muhammed YAYLA***, Sezen HARMANKAYA****, Murat BEYTUR*****, Cem ÖZİÇ******

* ORCID: 0000-0001-9923-6723, Department of Chemistry, Faculty of Science and Letter, Kafkas University, Kars, Turkey.
** ORCID: 0000-0002-9826-2556, Department of Pharmacology, Faculty of Medicine, Kastamonu University, Kastamonu, Turkey.
*** ORCID: 0000-0002-0659-3084, Department of Pharmacology, Faculty of Medicine, Kafkas University, Kars, Turkey.
**** ORCID: 0000-0003-2498-5003, Department of Food Processing, Kars Vocational College, Kafkas University, Kars, Turkey.
***** ORCID: 0000-0002-7098-5592, Department of Chemistry, Faculty of Science and Letter, Kafkas University, Kars, Turkey.
****** ORCID: 0000-0001-5415-9277, Department of Medical Biology, Faculty of Medicine, Kafkas University, Kars, Turkey
° Corresponding Author; Ahmet HARMANKAYA
E-mail: ahmet.harmankaya@kafkas.edu.tr

Pages 129-142, Abstract , PDF (1398 KB)

Design, Development, and Characterization of Lyophilized Posaconazole-Loaded Mixed Micelles for Improved Fungal Treatment and Stability

Adesh KURANE*, Rutuja CHOUGALE**, Vibhuti THAKUR***, Kiran PATIL****°, Shalaka PATKI*****, John Disouza******, Ashok HAJARE*******

* ORCID: 0009-0004-9408-9399, Department of Quality Assurance, Tatyasaheb Kore College of Pharmacy, Warananagar – 416113, Shivaji University,
Kolhapur-416004, Maharashtra, India.
** ORCID: 0000-0002-6312-8066, Department of Quality Assurance, Bharati Vidyapeeth College of Pharmacy, Kolhapur- 416013, Shivaji University,
Kolhapur-416004, Maharashtra, India.
*** ORCID: 0009-0009-9963-4743, Department of Quality Assurance, Tatyasaheb Kore College of Pharmacy, Warananagar – 416113, Shivaji University,
Kolhapur-416004, Maharashtra, India.
**** ORCID: 0000-0002-3248-6063, Department of Quality Assurance, Tatyasaheb Kore College of Pharmacy, Warananagar – 416113, Shivaji University,
Kolhapur-416004, Maharashtra, India.
***** ORCID: 0009-0009-2862-9015, Department of Pharmaceutics, Tatyasaheb Kore College of Pharmacy, Warananagar – 416113, Shivaji University,
Kolhapur-416004, Maharashtra, India.
****** ORCID: 0000-0002-9807-7932, Department of Pharmaceutics, Tatyasaheb Kore College of Pharmacy, Warananagar – 416113, Shivaji University,
Kolhapur-416004, Maharashtra, India.
******* ORCID: 0000-0002-2728-6155, Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Palus, Sangli- 416310, Dr. Babasaheb Ambedkar
Technological University, Lonere, Maharashtra, India.
° Corresponding Author; Kiran S. Patil
E-mail: kspatil.tkcp@gmail.com

Pages 143-162, Abstract , PDF (2897 KB)

Bilayer Nanofiber Scaffold Incorporated with Mupirocin and Thyme Essential Oil for Synergistic Activity Against Bacterial Wound Infections

Kisan JADHAV*º , Shivani GHARAT **, Shradha B. ADHALRAO***

* ORCID: 0000-0001-7563-3935, Department of Pharmaceutics, Bharati Vidyapeeth’s College of Pharmacy, Sector 3A, CBD Belapur, Navi Mumbai-400614,
Maharashtra. India.
** ORCID: 0000-0003-4972-8863, Department of Pharmaceutics, Bharati Vidyapeeth’s College of Pharmacy, Sector 3A, CBD Belapur, Navi Mumbai-400614,
Maharashtra. India.
*** ORCID: 0000-0002-6065-1839,Department of Pharmaceutics, Bharati Vidyapeeth’s College of Pharmacy, Sector 3A, CBD Belapur, Navi Mumbai-400614,
Maharashtra. India.
° Corresponding Author; Dr. Kisan Jadhav
Email ID: krj24@rediffmail.com

Pages 163-180, Abstract , PDF (2082 KB)

Protective Role of Pistacia palaestina Boiss. Fruit and Leaf Extracts in Isoproterenol-Induced Cardiac Ischemia

Mehmet Sina İÇEN*, Hande YÜCE**, Neşe BAŞAK TÜRKMEN***, Aslı TAŞLIDERE****, Dilan AŞKIN ÖZEK*****°, Songül ÜNÜVAR******

* ORCID: 0000-0002-1411-7184, Department of Pharmacognosy Faculty of Pharmacy, Inonu University, Malatya, Turkiye.
** ORCID: 0000-0003-2907-2019, Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Inonu University, Malatya, Türkiye.
*** ORCID: 0000-0001-5566-8321, Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Inonu University, Malatya, Türkiye.
**** ORCID: 0000-0003-3902-3210, Department of Histology and Embryology, Faculty of Medicine, Inonu University, Malatya, Türkiye.
***** ORCID: 0000-0001-9075-4807, Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Inonu University, Malatya, Türkiye.
****** ORCID: 0000-0001-8454-490X, Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Inonu University, Malatya, Türkiye.
° Corresponding Author: Dilan AŞKIN ÖZEK
E-mail: daskin@fırat.edu.tr

Pages 181-196, Abstract , PDF (11360 KB)

Comparative Study of The Anti-Inflammatory Pathway Enzyme Activities of Selected Plant Extracts from Lamiaceae Family

Kubra SENER *, Murat EKİCİ**, Ekrem Murat GONULALAN***, Ebru BODUR****°

* ORCID:0000-0002-8759-9444, Gazi University, Faculty of Science, Department of Biology, Ankara, Türkiye
** ORCID: 0000-0002-3402-177X, Gazi University, Faculty of Science, Department of Biology, Ankara, Türkiye
*** ORCID: 0000-0002-8171-3824, Afyonkarahisar Health Sciences University, Faculty of Pharmacy, Department of Pharmacognosy, Afyonkarahisar, Türkiye
**** ORCID:0000-0001-5829-5487, Hacettepe University, Faculty of Medicine Department of Medical Biochemistry, Ankara, Türkiye
° Corresponding Author: Ebru BODUR
E-mail: bodurebru@yahoo.com

Pages 197-210, Abstract , PDF (594 KB)

Financial Development of the Turkish Pharmaceutical Sector During and After the Pandemic: Sector Panel Data Analysis for the Period 2018-2022

Mustafa ÖZYEŞİL*°, Havane TEMBELO**

* ORCID: 0000-0002-4442-7087, İstanbul Aydın Üniversitesi, Anadolu Bil Meslek Yüksekokulu, İşletme Yönetimi (İngilizce), mozyesil@aydin.edu.tr
** ORCID: 0000-0003-3394-4166, İstanbul Aydın Üniversitesi, Lisansüstü Eğitim Enstitüsü, İşletme, havanetembelo@stu.aydin.edu.tr
° Corresponding Author; Mustafa ÖZYEŞİL
E-mail: mozyesil@aydin.edu.tr

Pages 211-226, Abstract , PDF (817 KB)

The Inhibitory Effect of Trimethylamine (TMA), an Intestinal Bacterial Metabolite, on Endothelial Vasorelaxation in Rat Mesenteric Artery

Melike Hacer ÖZKAN*º

* ORCID: 0000-0003-1339-2616, Hacettepe Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmakoloji A.B.D.
° Corresponding Author; Melike Hacer ÖZKAN
E-mail: melikeo@hacettepe.edu.tr

Pages 227-232, Abstract , PDF (199 KB)

Effect of n-Hexane Extract from Tanacetum argenteum (Lam.) Willd. subsp. argenteum on the Secretion of Proinflammatory Cytokines in THP-1 Cell Line

Ege ARZUK*°, Fuat KARAKUŞ**, Gökay ALBAYRAK***, Ali ERGÜÇ****, İclal TAN*****, Ecrin ATIŞ ******

* ORCID: 0000-0002-3239-4855, Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Ege University, İzmir, Türkiye
** ORCID: 0000-0002-5260-3650, Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Van Yüzüncü Yıl University, Van, Türkiye
*** ORCID: 0000-0002-5729-0796, Department of Pharmaceutical Botany, Faculty of Pharmacy, İzmir Kâtip Çelebi University, İzmir, Türkiye
**** ORCID: 0000-0002-9791-4399, Department of Pharmaceutical Toxicology, Faculty of Pharmacy, İzmir Kâtip Çelebi University, İzmir, Türkiye
***** ORCID: 0009-0001-2006-5480, Faculty of Pharmacy, Ege University, İzmir, Türkiye
****** ORCID: 0009-0001-8475-8067, Faculty of Pharmacy, Ege University, İzmir, Türkiye
° Corresponding Author; Ege ARZUK
E-mail: egearzuk@gmail.com

Pages 233-244, Abstract , PDF (1089 KB)

Review Articles
Endocrine Disrupting Effects of Flame Retardants on Thyroid System

İrem İYİGÜNDOĞDU*, İsmet ÇOK**°

* ORCID: 0000-0001-9780-2488, Dept. of Toxicology, Faculty of Pharmacy, Gazi University, Ankara, Turkey.
** ORCID: 0000-0003-3128-677X, Dept. of Toxicology, Faculty of Pharmacy, Gazi University, Ankara, Turkey.
° Corresponding Author: İsmet ÇOK
E-mail: ismetc@gazi.edu.tr, ismetcok@gmail.com

Pages 245-262, Abstract , PDF (268 KB)

 


This work is licensed under Attribution 4.0 International