Son Sayı

2023 Cilt 48, Sayı 3

İçindekiler, Sayı Kapağı, Yayın Kurulu
Bu sayı Ekim 2023’de elektronik olarak yayınlanmıştır.

İÇİNDEKİLER

Araştırma Makaleleri

48-03

Design and Assessment of a Microemulsion-Based Transdermal Drug Delivery System for Meloxicam; Examination of Formulation Ingredients

Anayatollah SALIMI*, Ramin NOORAFROOZ**, Maryam FOULADI***, Saeed Mohammad SOLEYMANI****º

* ORCID: 0000-0003-1505-7969, Department of Pharmaceutics, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Nanotechnology
Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz,
** ORCID: 0000-0000-0000-0000, Department of Pharmaceutics, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
*** ORCID: 0000-0000-0000-0000, Department of Pharmaceutics, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
**** ORCID: 0000-0003-1462-3930, Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

° Corresponding Author: Saeed Mohammad SOLEYMANI
Telephone number: +98-21-66355959,Email Address: mamsoloni@gmail.com

Sayfalar 359-372,  Öz , PDF (789 KB)

Evaluation of The Effect of Topotecan, Carvacrol, Epigallocatechin Gallate and Their Combination on Apoptotic Process in Neuroblastoma and Astrocyte Cells

Çağatay OLTULU*°, Melek AKINCI**, Elvan BAKAR***

* ORCID: 0000-0002-6051-3479, Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Trakya University, Edirne, Turkey.
** ORCID: 0000-0003-3879-4232, Department of Pharmacology, Faculty of Pharmacy, Trakya University, Edirne, Turkey.
*** ORCID: 0000-0001-5703-3469, Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Trakya University, Edirne, Turkey.

° Corresponding Author: Çağatay OLTULU
Phone: +90 (284) 235 01 80, E-mail: cagatayo@trakya.edu.tr

Sayfalar 373-384,  Öz , PDF (1MB)

Development and Characterization of Nanofiber Strip Containing Sertraline for Buccal Application

Kutsal ÖZCAN*, Eylül Su SARAL ACARCA**, Sibel ILBASMIS-TAMER***°

* ORCID: 0000-0001-5047-7251: Department of Pharmaceutical Technology, Faculty of Pharmacy, Gazi University, Ankara, Türkiye,
Faculty of Pharmacy, Department of Pharmaceutical Technology, Karadeniz Technical University, Trabzon, Turkey
** ORCID: 0000-0002-6497-1645: Department of Pharmaceutical Technology, Faculty of Pharmacy, Gazi University, Ankara, Türkiye
*** ORCID: 0000-0003-0361-7105: Department of Pharmaceutical Technology, Faculty of Pharmacy, Gazi University, Ankara, Türkiye

° Corresponding Author; Sibel İLBASMIŞ TAMER
Phone: 0 312 202 3056, E-mail: ilbasmis@gazi.edu.tr, ilbasm@yahoo.com

Sayfalar 385-394,  Öz , PDF (907KB)

Synthesis and Biological Evaluation of Novel Paracetamol-Triazole Conjugates

Necla KULABAŞ*, Merve GÜRBOĞA**, Özlem BİNGÖL ÖZAKPINAR***,
Jianyang LIU****, Per-Johan JAKOBSSON*****, Özkan DANIŞ******, Ayşe OGAN*******,
İlkay KÜÇÜKGÜZEL********°

* ORCID: 0000-0003-2273-5094, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Marmara University, Başıbüyük, İstanbul, Türkiye
** ORCID: 0000-0003-4614-7094, Department of Biochemistry, Faculty of Pharmacy, Marmara University, Başıbüyük, İstanbul, Türkiye
*** ORCID: 0000-0003-0287-563, Department of Biochemistry, Faculty of Pharmacy, Marmara University, Başıbüyük, İstanbul, Türkiye
**** ORCID: 0000-0002-8683-1109, Rheumatology Division, Department of Medicine, Solna, Karolinska Institutet & Karolinska University Hospital, Stockholm, Sweden
***** ORCID: 0000-0001-7665-9715, Rheumatology Division, Department of Medicine, Solna, Karolinska Institutet & Karolinska University Hospital, Stockholm, Sweden
****** ORCID: 0000-0003-1781-0520, Department of Chemistry, Faculty of Science, Marmara University, İstanbul, Türkiye
******* ORCID: 0000-0002-8973-9762, Department of Chemistry, Faculty of Science, Marmara University, İstanbul, Türkiye
******* ORCID: 0000-0002-7188-1859 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Fenerbahçe University, Ataşehir, İstanbul, Türkiye

° Corresponding Author;İlkay KÜÇÜKGÜZEL
Tel: +90 216 910 1907 , E-mail: kucukguzel@hotmail.com, ilkay.kucukguzel@fbu.edu.tr

Sayfalar 395-410,  Öz , PDF (760KB)

Interpretable QSAR Modelling for QSAR-Based Virtual Screening of 3H-Thiazolo[4,5-b] pyridin-2-one Derivatives as Potential Antioxidant Drug Candidates

Olena KLENINA*°

* Orcid ID: 0000-0002-8946-3698, Department of General, Bioinorganic, Physical and Colloidal Chemistry, Faculty of Pharmacy, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine; Departament of Chemistry and Biochemistry, Faculty of Pharmacy, University San Pablo-CEU, Urbanización Montepríncipe, 28668 Boadilla del Monte, España

° Corresponding Author; Olena Klenina
Phone: +380 980 519 298, E-mail: olena_klenina@yahoo.com

Sayfalar 411-430,  Öz , PDF (697KB)

Phase Transformation of Anhydrous to Dihydrate Carbamazepine: Preparation and Comparative Characterization

Kamlesh WADHER*°, Vaishnavi RAUT**, Keshav HIRAVE***, Sagar TRIVEDI****,
Milind UMEKAR*****

* ORCID:0000-0002-3782-3380, Department of Pharmaceutics, Smt. KishoritaiBhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India 441002.
** ORCID: 0009-0002-2936-1849,Department of Pharmaceutics, Smt. KishoritaiBhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India 441002.
*** ORCID: 0000-0001-5673-3105 ,Department of Pharmaceutics, Smt. KishoritaiBhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India 441002.
**** ORCID: 0000-0001-6764-0019,Department of Pharmaceutics, Department of Pharmaceutical Sciences, RashtrasantTukadoji Maharaj Nagpur University
Campus, Nagpur, India
***** ORCID: 0000-0002 2170-0896,Department of Pharmaceutics, Smt. KishoritaiBhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India 441002.

° Corresponding Author; Prof. Kamlesh Wadher
Mob. No. +91 9960099619, Email ID: kamleshwadher@gmail.com

Sayfalar 431-442,  Öz , PDF (1MB)

Anticancer Potential of Novel Nanoemulgel Formulations in Melanoma

Selin Seda TİMUR°*

* ORCID: 0000-0001-9010-3457, Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology, 06100-Ankara, Turkey.

° Corresponding Author;Selin Seda TİMUR
Telephone: +903123051241; E-mail: selins.dogan@hacettepe.edu.tr

Sayfalar 443-458,  Öz , PDF (1MB)

Synthesis of Some Novel Schiff Base Derivative 5-Substituted-4-Amino-1,2,4-Triazole-3-one Compounds with Potential Lipase Inhibition Activity

Yaren KAHVECİ*, İnci Selin DOĞAN**°, Şeyda KANBOLAT***, Bahittin KAHVECİ****

* ORCID: 0000-0002-4709-2278, Hacettepe University, Faculty of Pharmacy, Ankara, Turkey
** ORCID:: 0000-0003-4949-1747, Karadeniz Technical University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Trabzon, Turkey
*** ORCID:: 0000-0001-7261-7067, Karadeniz Technical University, Faculty of Pharmacy, Department of Biochemistry, Trabzon, Turkey
**** ORCID:: 0000-0001-7394-0552, Karadeniz Technical University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Trabzon, Turkey

° Corresponding Author;Assoc. Prof.Dr. İnci Selin DOĞAN
Phone: 0532 609 28 85, E-mail: isdogan@ktu.edu.tr, selinci@gmail.com

Sayfalar 459-468,  Öz , PDF (343KB)

Gene Delivery to Triple-Negative Breast Cancer Cells by Folic Acid-Polyethyleneimine Polyplexes

Devrim DEMIR-DORA *,**,***º

* ORCID: 0000-0002-6610-2507, Department of Medical Pharmacology, Faculty of Medicine, Akdeniz University, Antalya, Turkey,
** ORCID: 0000-0002-6610-2507, Department of Gene and Cell Therapy, Health Sciences Institute, Akdeniz University, Antalya, Turkey
*** ORCID: 0000-0002-6610-2507, Department of Medical Biotechnology, Health Sciences Institute, Akdeniz University, Antalya, Turkey

° Corresponding Author; Devrim DEMİR-DORA
Phone: +90-532-4133477, e-mail: dedemir@yahoo.com

Sayfalar 469-480,  Öz , PDF (627KB)

NLRP3 Expression in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis

Sezen Yılmaz SARIALTIN*°, Orhan KÜÇÜKŞAHIN**, Cemil NURAL***, Leyla Didem KOZACI****, Pınar KAYGIN*****, Gülçin GÜLER ŞİMŞEK******, Serpil OĞUZTÜZÜN*******, Tülay ÇOBAN ********

* ORCID: 0000-0002-8387-4146: Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Ankara University, Ankara, Turkiye
** ORCID: 0000-0003-4530-2304: Division of Rheumatology, Department of Internal Medicine, Ankara Yıldırım Beyazıt University, Ankara, Turkiye
*** ORCID: 0000-0002-7867-7615: Department of Biochemistry, Hatay Training and Research Hospital, Hatay, Turkiye
**** ORCID: 0000-0001-5422-1640: Department of Medical Biochemistry, Faculty of Medicine, Ankara Yıldırım Beyazıt University, Ankara, Turkiye
***** ORCID: 0000-0003-0127-1753: Department of Biology, Faculty of Art and Sciences, Kırıkkale University, Kırıkkale, Turkiye
****** ORCID: 0000-0001-7710-4631: Department of Pathology, Gülhane Training and Research Hospital, University of Health Sciences, Ankara, Turkiye
******* ORCID: 0000-0002-5892-3735: Department of Biology, Faculty of Art and Sciences, Kırıkkale University, Kırıkkale, Turkiye
******** ORCID: 0000-0002-9696-6613: Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Ankara University, Ankara, Turkiye

° Corresponding Author; Sezen YILMAZ SARIALTIN
Phone: +903122033121, e-mail: sezen.yilmaz@ankara.edu.tr

Sayfalar 481-492,  Öz , PDF (1MB)

Drug Administration via Feeding Tube in Intensive Care Unit: A Cross-Sectional Study

Nursel SÜRMELİOĞLU*°, Yaren İLERİ**, Murat GÜNDÜZ***, Dilek ÖZCENGİZ****

* ORCID:0000-0001-7758-7100, Department of Clinical Pharmacy, Faculty of Pharmacy, Çukurova University, Adana, Türkiye, e-mail: nurselisci@gmail.com
** ORCID:0009-0008-1014-3474, Department of Clinical Pharmacy, Faculty of Pharmacy, Marmara University, İstanbul, Türkiye, e-mail: yarenileri01@gmail.com
*** ORCID:0000-0003-0006-8796, Department of Anesthesia and Reanimation, Faculty of Medicine, Çukurova University, Adana, Türkiye, e-mail: hmuratgunduz@gmail.com
**** ORCID:0000-0002-2598-0127, Department of Anesthesia and Reanimation, Faculty of Medicine, Çukurova University, Adana, Türkiye, e-mail: dilekozcengiz@gmail.com

° Corresponding Author; Nursel SÜRMELİOĞLU
Phone: +905330546901, e-mail: nurselisci@gmail.com

Sayfalar 493-500,  Öz , PDF (256KB)

Association of Inflammatory Parameters with Survival in Gastric Cancer Patients Underwent Subtotal and Total Gastrectomy

Bercis Imge UCAR*°, Muhammed Alperen TAŞ**, Hüseyin Emre ARSLAN***,
Mehmet Fatih EKICI****, Sezgin ZEREN*****

* ORCID: 0000-0003-0229-5589, Department of General Surgery, Faculty of Medicine, Kutahya Health Sciences University, 43000 Kutahya
** ORCID: 0000-0002-4060-121X, Department of General Surgery, Faculty of Medicine, Kutahya Health Sciences University, 43000 Kutahya
*** ORCID: 0000-0002-3937-825X, Department of General Surgery, Faculty of Medicine, Kutahya Health Sciences University, 43000 Kutahya
**** ORCID: 0000-0002-3937-825X, Department of General Surgery, Faculty of Medicine, Kutahya Health Sciences University, 43000 Kutahya
***** ORCID: 0000-0002-9342-1706, Department of General Surgery, Faculty of Medicine, Kutahya Health Sciences University, 43000 Kutahya

° Corresponding Author; Bercis Imge UCAR
Phone: +902742316660, e-mail: bercis.imge@gmail.com

Sayfalar 501-512,  Öz ,PDF (380KB)

In Silico and In Vitro Anticancer Effects of Caffeic Acid Phenethyl Ester on Pancreatic Adenocarcinoma Cells

Zübeyde TANRIVERDİ*, Burak KUZU**, Ergül EYOL***, Fuat KARAKUŞ****°

* ORCID:0000-0002-1170-181X: Independent Researcher, Gaziantep/Türkiye.
** ORCID: 0000-0002-7305-7177: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Van Yuzuncu Yil University, 65080 Tuşba-Van/Türkiye.
*** ORCID: 0009-0000-3699-6725: Independent Researcher, Mannheim /Germany.
**** ORCID: 0000-0002-5260-3650: Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Van Yuzuncu Yil University, 65080 Tuşba-Van/Türkiye.

° Corresponding Author; Fuat Karakuş
Tel.: +90 432 444 5065 Extension: 2118, E-mail:fuatkarakus@yyu.edu.tr

Sayfalar 513-522,  Öz , PDF (2MB)

Metabolomic Studies in Girls With Central and Peripheral Precocious Puberty

Aylin BALCI OZYURT*, Tuba REÇBER**, Emirhan NEMUTLU***, Ayse Derya BULUS****, Sedef KIR*****, Belma KOCER-GUMUSEL******°, Pinar ERKEKOGLU*******°

* ORCID:0000-0002-0060-271X: Hacettepe University, Faculty of Pharmacy, Department of Toxicology, Ankara, Turkey; Bahçeşehir University, School of
Pharmacy, Department of Toxicology, İstanbul, Turkey
** ORCID: 0000-0001-8257-7628: Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry, Ankara, Turkey
*** ORCID: 0000-0002-7337-6215: Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry, Ankara, Turkey
**** ORCID: 0000-0003-2865-4420: The Ministry of Health, Keçiören Training and Research Hospital, Pediatric Endocrinology Clinics, Ankara, Turkey
***** ORCID: 0000-0003-1322-1665: Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry, Ankara, Turkey
****** ORCID: 0000-0003-4311-2291: Lokman Hekim University, Faculty of Pharmacy, Department of Toxicology, Ankara, Turkey
******* ORCID: 0000-0003-4713-7672: Hacettepe University, Faculty of Pharmacy,

Department of Toxicology, Ankara, Turkey
° Corresponding Author;Pınar ERKEKOĞLU
Phone: 0312 305 2178, e-mail: erkekp@yahoo.com, erkekp@hacettepe.edu.tr

° Corresponding Author; Belma KOCER-GUMUSEL
Phone: 0312 502 8558, e-mail: belmagumusel@yahoo.com, belma.gumusel@lokmanhekim.edu.tr

Sayfalar 523-538,  Öz , PDF (1MB)

Hydrogen Sulfide Promotes Wound Healing by Attenuating Reactive Oxygen Species in Fibroblasts under Hyperglisemic Conditions

Merve DENİZALTI *º

* ORCID: 0000-0001-5363-606X, Hacettepe University, Faculty of Pharmacy, Department of Pharmacology, Ankara, Turkey

° Corresponding Author; Merve Denizaltı
Phone: +90 312 305 2131,E-mail: denizalt@hacettepe.edu.tr

Sayfalar 539-548,  Öz , PDF (352KB)

Phenethyl isothiocyanate Regulates the Cancer Stem Cell Phenotype of SNU449 Hepatocellular Carcinoma Cells via STAT3-CD44 Axis

Basri SATILMIŞ*º

* ORCID: 0000-0002-2538-5774, Hepatology Research Laboratory, Liver Transplant Institute, Inonu University, Malatya, Turkey.

° Corresponding Author; Basri SATILMIŞ
Phone: +90 422 34106660/6060, e-mail:basri.satilmis@inonu.edu.tr

Sayfalar 549-560,  Öz , PDF (1MB)

Derleme Makaleleri
Mucoadhesive Drug Delivery Systems for Pediatric and Geriatric Patients

Arya RAI*, Shristhi Sohan RAWAT**, Ritu RATHI***, Deepika RAINA****, Oluwatoyin Adepeju ODEKU*****, Inderbir SINGH******

* ORCID: Chitkara College of Pharmacy, Chitkara University, Punjab, India
** ORCID: Chitkara College of Pharmacy, Chitkara University, Punjab, India
*** ORCID: Chitkara College of Pharmacy, Chitkara University, Punjab, India
**** ORCID: School of Pharmacy, Graphic Era Hill University, Dehradun, Uttarakhand, India
***** ORCID: Department of Pharmaceutics and Industrial Pharmacy, University of Ibadan, Nigeria
****** ORCID: Chitkara College of Pharmacy, Chitkara University, Punjab, India

° Corresponding Author; Inderbir Singh
E-mail: inderbir.singh@chitkara.edu.in

Sayfalar 561-584,  Öz, PDF (1MB)

 


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