Last Issue

2024 Volume 49, Issue 3

Contents, Issue Cover, Editorial Board
This issue was published electronically in October 2024.

CONTENT 

Research Articles

49-3

Evaluation of the Genotoxic Impurities of Selpercatinib
Through HPLC and LC-MS/MS Identification of
Selpercatinib Stress Degradation Products
Bheemireddy DIVYA*, J Murali PRAKASH**, Eevana Venkata CHIRANJEEVI***,
Bhaskara Rao TADIBOINA****°

* ORCID: , Department of Chemistry, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur – 522302, A.P., India
** ORCID: , Department of Chemistry, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur – 522302, A.P., India
*** ORCID: , Department of Organic Chemistry, Sri Y.N.M College (Autonomous), Narsapur – 534275, AP, India
**** ORCID: , Department of Chemistry, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur – 522302, A.P., India
° Corresponding Author; Bhaskara Rao Tadiboina
E-mail: tbhaskararao@gmail.com

Sayfalar 449-464, Abstact , PDF (514 KB)


The Local Anesthetic Activity of 4-(Naphthalen-1-yloxy)But-2-yn-1-
yl)-Containing Piperidine Derivatives in Experimental Animal Models
* ORCID: 0000-0001-6775-4358, Department of Pharmacology, Faculty of General Medicine -1, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
** ORCID: 0000-0002-8409-2672, Laboratory of Physiologically Active Compounds chemistry, A.B. Bekturov Institute of Chemical Sciences, Almaty, Republic of Kazakhstan.
*** ORCID: 0000-0002-8317-7914, Department of Pharmacology, Faculty of General Medicine -1, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
**** ORCID: 0000-0002-5521-5776, Department of Pharmacology, Faculty of General Medicine -1, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
***** ORCID: 0000-0001-6508-707X, Laboratory of Synthetic and Natural Medicinal Compounds Chemistry, A.B. Bekturov Institute of Chemical Sciences, Almaty, Republic of Kazakhstan.
****** ORCID: 0000-0002-8036-604X, Department of Pharmacology, Faculty of General Medicine -1, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
******* ORCID: 0000-0003-2210-708X, Institute of Physiology and Pharmacology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
******** Orcid: 0000-0002-4184-4758, Department of Pharmacology, Faculty of General Medicine -1, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
********* ORCID: 0000-0003-4312-9093, Faculty of General Medicine -2, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan.
********** ORCID: 0000-0002-1067-5162, Laboratory of Synthetic and Natural Medicinal Compounds Chemistry, A.B. Bekturov Institute of Chemical Sciences, Almaty, Republic of Kazakhstan.
° Corresponding Author; Malika Khaiitova
E-mail: khaiitova.m@kaznmu.kz
Yelena Sycheva
E-mail: yelena-sycheva@yandex.kz

Sayfalar 465-480, Abstact , PDF (975 KB)


Assessment of the Antioxidant, Antiproliferative and
Antityrosinase Potential of Unripe Fruit of Prunus x
domestica
L.
Zühal BAYRAKÇEKEN GÜVEN*°, Neslihan YUCE**, A. Ahmet BASARAN***

* ORCID: 0000-0003-3405-6996, Department of Pharmacognosy, Faculty of Pharmacy, Erzincan Binali Yıldırım University, Erzincan, Turkey
** ORCID: 0000-0001-6878-064, Department of Medical Biochemistry, Faculty of Medicine, Ataturk University, Erzurum, Turkey
*** ORCID: 0000-0001-8570-9649, Department of Pharmacognosy, Faculty of Pharmacy, Baskent University, Ankara, Turkey
° Corresponding Author; Zühal Bayrakçeken Güven
E-mail: zhlbayrakceken@gmail.com

Sayfalar 481-490, Abstact , PDF (311 KB)


99mTc-Labeled Microsized Liposomes

Helin HEKIMOGLU*+, Merve KARPUZ**°+, Emre OZGENC***,
Evren GUNDOGDU****

* ORCID ID: 0009-0001-7119-6878. Izmir Katip Celebi University Faculty of Pharmacy, Izmir, Turkey.
** ORCID ID: 0000-0001-6681-2448. Izmir Katip Celebi University Faculty of Pharmacy, Department of Radiopharmacy, Izmir, Turkey.
*** ORCID ID: 0000-0002-7586-8520. Ege University Faculty of Pharmacy, Department of Radiopharmacy, Izmir, Turkey.
**** ORCID ID: 0000-0003-2111-101X. Ege University Faculty of Pharmacy, Department of Radiopharmacy, Izmir, Turkey.
+ These authors contributed equally.
° Corresponding Author; Merve KARPUZ,
e-mail: merve.karpuz@ikcu.edu.tr

Sayfalar 491-504, Abstact , PDF (601 KB)


A Novel Method for The Simultaneous Determination
of Olanzapine and Escitalopram in Artificial Saliva by
High Performance Liquid Chromatography
Aysun DİNÇEL*°, Selin ŞAMİL**, E. Damla GÖK-TOPAK***

* ORCID: 0000-0002-1986-6862: Lokman Hekim University, Faculty of Pharmacy, Department of Analytical Chemistry, 06510, Ankara, Türkiye
** ORCID: 0009-0005-0650-5477: Lokman Hekim University, Faculty of Pharmacy, Department of Analytical Chemistry, 06510, Ankara, Türkiye
*** ORCID: 0000-0002-2586-8207: Lokman Hekim University, Faculty of Pharmacy, Department of Analytical Chemistry, 06510, Ankara, Türkiye
° Corresponding Author; Aysun DİNÇEL
E-mail: aysun.dincel@lokmanhekim.edu.tr

Sayfalar 505-512, Abstact , PDF (387 KB)


Does Functionality of Perivascular Adipose Tissue
Decrease in the Adult Rat Thoracic Aorta?
Gaye OZTURK*, Melike Hacer OZKAN**°

* ORCID: 0000-0002-2073-7865, Private Mim Hospital, Cankaya, Ankara, Turkiye
** ORCID: 0000-0003-1339-2616, Department of Pharmacology, Faculty of Pharmacy, Hacettepe University, Sihhiye, Ankara, Turkiye
° Corresponding Author; Melike Hacer OZKAN
E-mail: melikeo@hacettepe.edu.tr

Sayfalar 513-524, Abstact , PDF (283 KB)


Evaluation of Antioxidant, Cytotoxic Effects and
Phytochemical Profiles of Galls Caused by Eriophyidae
mite in Juglans regia Leaves
Semih BULUT*°, Burçin ÖZÜPEK**, Sultan PEKACAR***, Aysun ÖZDEMİR****,
Didem DELİORMAN ORHAN*****

* ORCID: 0000-0002-4098-0221, Department of Pharmacognosy, Faculty of Pharmacy, Suleyman Demirel University, Isparta, Turkiye
** ORCID: 0000-0003-2159-9860, Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkiye
*** ORCID: 0000-0002-7782-9832, Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkiye
**** ORCID: 0000-0003-0311-0507, Department of Pharmacology, Faculty of Pharmacy, Gazi University, Ankara, Turkiye
***** ORCID: 0000-0003-3916-4048, Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkiye
° Corresponding Author; Semih BULUT
E-mail: semihbulut@sdu.edu.tr

Sayfalar 525-538, Abstact , PDF (530 KB)


A (hetero)arylidene-(4-substituted-thiazol-2-yl)
hydrazine As New Potential MAO-B inhibitors.
Computational Study and In-Silico Prediction
Moulay Ahfid El ALAOUY*, Marwa ALAQARBEH**°, Abdelouahid SBAI***,
Hamid MAGHAT****, Tahar LAKHLIFI*****, Mohammed BOUACHRINE******

* ORCID: 0009-0005-1593-1486 Molecular Chemistry and Natural Substances Laboratory, Faculty of Science, University Moulay Ismail, Meknes, Morocco
** ORCID: 0000-0002-0879-5077 Basic Science Department, Prince Al Hussein bin Abdullah II Academy for Civil Protection, Al-Balqa Applied University, Al-Salt 19117, Jordan
*** ORCID: 0000-0002-7140-9853 Molecular Chemistry and Natural Substances Laboratory, Faculty of Science, University Moulay Ismail, Meknes, Morocco
**** ORCID: 0000-0002-7731-330X Molecular Chemistry and Natural Substances Laboratory, Faculty of Science, University Moulay Ismail, Meknes, Morocco
***** ORCID: 0000-0003-4917-475X Molecular Chemistry and Natural Substances Laboratory, Faculty of Science, University Moulay Ismail, Meknes, Morocco
****** ORCID: 0000-0002-8901-047X Molecular Chemistry and Natural Substances Laboratory, Faculty of Science, University Moulay Ismail, Meknes, Morocco
° Corresponding Author; Marwa Alaqarbeh,
marwaqarbh@hotmail.com; marwa.aqarbeh@bau.edu.jo

Sayfalar 539-564, Abstact , PDF (1.835 KB)


Innovative Approaches in Mirtazapine Delivery: Pharmacokinetic
Simulations, Immediate Release to Controlled-Release Tablets,
Formulation Optimization via D-optimal Mixture Design
Srk Raju SAGIRAJU*°, Pankaj Kumar SHARMA**, Jaya SHARMA***

* ORCID: 0009-0003-8844-4633, Research Scholar of Pharmacy, Apex university, Jaipur, Rajasthan,302018, India
** ORCID: 0000-0001-7398-2744, Dean of Pharmacy, Apex University, Jaipur, Rajasthan,302018, India
*** ORCID:0000-0002-1406-6225, Principal School of Pharmacy, Apex University, Jaipur, Rajasthan, India
° Corresponding Author; SRK Raju Sagiraju
E-mail: raaju42@gmail.com

Sayfalar 565-582, Abstact , PDF (584 KB)


Review Articles

The Rise of Artificial Intelligence in Pharma: Shaping
the Future of Drug Discovery
Ayca DEDEOGLU-ERDOGAN*°, Armanc MAT**, Enise Ece GURDAL***,
Meric KOKSAL****

* ORCID: 0000-0001-5936-5328, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, Atasehir, 34755 Istanbul, Turkey
** ORCID: 0009-0001-8379-3987, Faculty of Pharmacy, Yeditepe University, Atasehir, 34755 Istanbul, Turkey
*** ORCID: 0000-0003-1064-8639, Department of Organic Chemistry, Faculty of Chemistry, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany
Department of Nano-optics, Max Planck Institute for the Science of Light, 91058, Erlangen, Germany
**** ORCID: 0000-0001-7662-9364, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, Atasehir, 34755 Istanbul, Turkey
° Corresponding Author; Ayca DEDEOGLU-ERDOGAN,
E-mail: elifaycadedeoglu@gmail.com

Sayfalar 583-602, Abstact , PDF (1.103 KB)


An Overview of Synthetic Derivatives of Thiazole and
Their Role in Therapeutics
Manoj KASHYAP*, Muslek Uddin MAZUMDER**°, Pooja PATOWARY***,
Apurba TALUKDAR****, Bhargab Jyoti SAHARIAH*****, Manish MAJUMDER******

*ORCID: 0000-0002-9675-8646, Department of Pharmaceutical Chemistry, NETES Institute of Pharmaceutical Science (NEMCARE Group of Institutions), Kamrup, Assam, India.
** ORCID: 0000-0002-1540-3086, Research Scholar, Assam Science and Technology University, Guwahati, Assam, India.
*** ORCID: 0000-0002-0476-2868, Department of Pharmaceutical Chemistry, NETES Institute of Pharmaceutical Science (NEMCARE Group of Institutions), Kamrup, Assam, India.
**** ORCID: 0000-0001-9538-2512, Department of Pharmaceutics, NETES Institute of Pharmaceutical Science (NEMCARE Group of Institutions), Kamrup, Assam, India.
***** ORCID: 0000-0003-0440-6983, Department of Pharmaceutics, NETES Institute of Pharmaceutical Science (NEMCARE Group of Institutions), Kamrup, Assam, India.
****** ORCID: 0000-0001-8035-7429, Department of Pharmaceutical Chemistry, NETES Institute of Pharmaceutical Science (NEMCARE Group of Institutions), Kamrup, Assam,
India.
° Corresponding Author; Muslek Uddin MAZUMDER
E-mail: muslekm@gmail.com

Sayfalar 603-626, Abstact , PDF (519 KB)


Ocular Drug Delivery Routes: Diseases Overview and
Advanced Administration Methods
Ceren YETGIN*, Fatma Nur TUĞCU-DEMİRÖZ**, Sevgi TAKKA***°

* ORCID: 0000-0001-6451-0497, Gazi University Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Turkey.
** ORCID: 0000-0002-9468-3329, Gazi University Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Turkey.
*** ORCID: 0000-0003-4429-9836, Gazi University Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Turkey.
° Corresponding Author; Sevgi TAKKA
E-mail: takka@gazi.edu.tr

Sayfalar 627-646, Abstact , PDF (609 KB)


Nanomaterials Marvels: Transformative Advancements
in Biomedicine, Drug Delivery, and Pharmaceutical
Analysis
Amaresh PRUSTY*°, Sasmita Kumari PADHİ**

* ORCID: 0000-0002-2978-8044, Department of Pharmaceutics, Royal College of Pharmacy and Health Sciences, Berhampur. Odisha. India.
** ORCID: 0009-0009-7989-1021, College of Nursing. MKCG College. Berhampur. Odisha. India.
° Corresponding Author; Dr. Amaresh Prusty
E-mail: amareshprusty@gmail.com

Sayfalar 647-658, Abstact , PDF (185 KB)


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